Silencing mechanisms of plant heterochromatin regions

我们分析了参与沉默植物基因组中内源重复元件的因子的功能。结果表明，存在3条独立的沉默通路，分别受(1)Morpheus‘s MOLECULE1(MOM1)、(2)RNA引导的DNA甲基化(RdDM)和(3)MOM1和RdDM共同调控。色域在拟南芥以外的植物的MOM1蛋白中普遍存在，但我们的分析表明，它对MOM1的沉默活性是必不可少的。

We analyzed function of factors involved in silencing of endogenous repetitive elements in the plant genome. The results suggested the presence of three independent silencing pathways regulated by(1) MORPHEUS' MOLECULE1(MOM1),(2) RNA-directed DNA methylation(RdDM), and(3) both of MOM1 and RdDM, respectively. Chromodomain is often found in MOM1 protein of plants other than Arabidopsis thaliana, but our analysis indicated that it is dispensable for silencing activity of MOM1.