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Functional coupling between Ca^<2+> influx anf Ca^<2+> release during Ca^<2+> oscillatons in fertilized mammalian eggs

Functional coupling between Ca^<2+> influx anf Ca^<2+> release during Ca^<2+> oscillatons in fertilized mammalian eggs
受精哺乳动物卵 Ca^<2> 振荡过程中 Ca^<2> 流入与 Ca^<2> 释放之间的功能耦合
批准号:
21590229
负责人:
SHIRAKAWA Hideki
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
To elucidate the regulatory mechanism for Ca^<2+> influx pathway in fertilized mammalian eggs, we conducted a series of molecular and physiological experiments to interfere the interactions between Ca^<2+> influx channels on the plasma membrane, TRPC and Orai, and proteins on the ER membrane, STIM. The results suggested that, although none of these proteins participate functionally in the maintenance of the Ca^<2+> oscillations by activating Ca^<2+> influx, STIM1 may have an novel role other than as an activator of store-operated Ca^<2+> entry.
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会议论文
Time-lapse observation of cytoplasmic actin filament in mouse eggs during fertilization.
受精过程中小鼠卵细胞质肌动蛋白丝的延时观察。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Kumakura, Y, Manabe, S., Shirakawa, H.]
通讯作者: H.
On the role of SIM/Orai pathway in Ca^<2+> entry during Ca^<2+> oscillations in fertilized mouse eggs
受精卵Ca^<2>振荡过程中SIM/Orai通路在Ca^<2>进入中的作用
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [高橋徹, 木所佑, 白川英樹]
通讯作者: 白川英樹
マウス卵におけるSTIM/Oraiタンパク質による細胞内Ca^<2+>濃度調節
STIM/Orai蛋白对小鼠卵细胞内Ca^2+浓度的调节
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [木所佑介, 日高裕華, 白川英樹]
通讯作者: 白川英樹
Characterization of Ca^<2+> influx pathway activated during Ca^<2+> oscillations in mouse eggs
小鼠卵中 Ca^<2> 振荡过程中激活的 Ca^<2> 流入途径的表征
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [高橋徹, 白川英樹]
通讯作者: 白川英樹
16
    Synthesis of Helical Polyacetylene and Construction of Molecular Solenoid
    • 批准号:
      10450359
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $1.92万
    • 财政年份:
      1998
    • 负责人:
      SHIRAKAWA Hideki
    • 依托单位:
    Synthesis and Properties of Liquid Crystalline Conducting Polymers
    Synthesis and Properties of One-Dimensional Conjugated Polymer (Carbyne).
    海外基金