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Specification and verification of periodontal pathogens relate to various vascular diseases

Specification and verification of periodontal pathogens relate to various vascular diseases
与各种血管疾病相关的牙周病原菌的规范和验证
批准号:
21592621
负责人:
UMEDA Makoto
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
The monoclonal antibodies effective for the detection of P. gingivalis and T. forsythia localized in tissue specimens were prepared. Periodontal pathogen was detected in diseased gingival tissue and atherosclerosis sample by immunohistochemistry. Oral and vascular samples of Buerger disease patients in Sri Lanka were detected periodontal pathogens by polymerase chain reaction method. The existence of periodontal pathogens in formalin-fixed and paraffin embedded lymph nodes proximal to oral cavity was examined from patients with histories of head and neck cancer. These bacteria invaded in gingival tissues might translocate peripheral arteries via lymph nodes.
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新規に開発したモノクローナル抗体を用いた病的歯肉組織中の歯周病原細菌の検出と局在
使用新开发的单克隆抗体检测和定位病理牙龈组织中的牙周病原菌
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [RajakarunaG Amodini, 内田佳介, 梅田誠, 古川あすか, 和泉雄一, 江石義信]
通讯作者: 江石義信
DOI: --
发表时间: 2014
期刊:
影响因子: --
作者: [Sato J, Nishimura M, Yamazaki M, Yoshida K, Kurashige Y, Saitoh M, Abiko Y., 青木 章,水谷幸嗣,和泉雄一(分担)]
通讯作者: 青木 章,水谷幸嗣,和泉雄一(分担)
Whole-blood platelet aggregation by Porphyromonas gingivalis in Patients with peripheral arterial disease
周围动脉疾病患者牙龈卟啉单胞菌引起的全血血小板聚集
DOI: --
发表时间: 2011
期刊: J Med and Dent Sci.
影响因子: --
作者: [Hiroyuki Notani, Yoshinori Inoue, Norihide Sugano, et al.]
通讯作者: et al.
The periodontal anaerobe porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model
牙周厌氧菌牙龈卟啉单胞菌通过大鼠模型诱导全血血小板活化和聚集增加
DOI: --
发表时间: 2011
期刊: Thromb Res
影响因子: 7.5
作者: [Kangmin Y, Inoue Y, Umeda M, Terasaki H, Chen Z, Iwai T]
通讯作者: Iwai T
11
    Strategy Foundation of Preemptive medicine for peri-implantitis of patients with diabetes mellitus
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    • 项目类别:
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    • 资助金额:
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    The colonization of periodontopathic bacteria in the oral cavity since childhood
    • 批准号:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
      1999
    • 负责人:
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    • 依托单位:
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