Development of the prevention program adapting 3DS from the systemic bacterial infection for the children under immunity control before Hemopoietic stem cell transplantation

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We developed a new oral prevention program adapting 3DS(Dental Drug Delivery System). When we applied the new program for the children under immunity control before Hemopoietic stem cell transplantation, the number of bacteria in the mouth decreased and it maintained the low value for 3 months. And the program made less inflammation of oral mucous membrane than usual. Therefore, the new 3DS prevention program can decrease the risk of the children' s systemic bacterial infection, and it can improve their Quality of Life.