Analysis of the expanding caries area mechanism by cigarette smoke exposure

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The exposure of cigarette smoke did not change amount of saliva, activity and growth of Streptococcus mutans and component of re-calcification part. The exposure of cigarette smoke temporarily decreased the Amylase and Peroxidase activity in saliva. In the cigarette smoke-exposed rats, vasodilation and hyperemia in the parotid grand and submandibular gland were observed by histological analysis. Inflammatory cells were not found infiltrating the salivary glands. The area of caries in the cigarette smoke exposure caries rats were significantly increasing compared with the caries rats.These results suggest that cigarette smoke exposure changes salivary component and expands caries area in the maxillary molars of rat.