Analysis of the expanding caries area mechanism by cigarette smoke exposure

香烟烟雾暴露对唾液量、变形链球菌的活性、生长及再钙化部分的成分无明显影响。香烟烟雾暴露可使唾液中淀粉酶和过氧化物酶活性暂时性降低。在香烟烟雾暴露的大鼠中，通过组织学分析观察到腮腺和下颌下腺的血管扩张和充血。未发现炎性细胞浸润唾液腺。香烟烟雾暴露组大鼠龋损面积较对照组明显增加，提示香烟烟雾暴露改变了大鼠上颌磨牙唾液成分，扩大了龋损面积。

The exposure of cigarette smoke did not change amount of saliva, activity and growth of Streptococcus mutans and component of re-calcification part. The exposure of cigarette smoke temporarily decreased the Amylase and Peroxidase activity in saliva. In the cigarette smoke-exposed rats, vasodilation and hyperemia in the parotid grand and submandibular gland were observed by histological analysis. Inflammatory cells were not found infiltrating the salivary glands. The area of caries in the cigarette smoke exposure caries rats were significantly increasing compared with the caries rats.These results suggest that cigarette smoke exposure changes salivary component and expands caries area in the maxillary molars of rat.