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Molecular mechanisms that determine kinetochore orientation acting at the heart of genome transition

Molecular mechanisms that determine kinetochore orientation acting at the heart of genome transition
决定作用于基因组转变核心的着丝粒方向的分子机制
批准号:
21000010
负责人:
WATANABE Yoshinori
金额:
$221.31万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Specially Promoted Research
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012

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中文摘要
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英文摘要
We have proven that cohesion at the core centromere defines mono-orientation of kinetochores. We show that chiasmata between homologous chromosomes ensure mono-orientation. We identified the kinase antagonizing shugoshin-PP2A. We further identified the inner centromere-shugoshin (ICS) network that is critical for chromosome segregation and the conserved regulatory mechanism of shaping chromosomes.
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DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Tension across centromeres refines centromeric protection by shugoshin
着丝粒间的张力通过 shugoshin 改善着丝粒保护
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Watanabe, Y]
通讯作者: Y
Aurora B mediated phosphorylation of hSgo2 is crucial for chromosome congression and centromeric protection
Aurora B 介导的 hSgo2 磷酸化对于染色体会聚和着丝粒保护至关重要
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Watanabe, Y]
通讯作者: Y
実験医学,31(6):減数分裂特異的コヒーシンと染色体異数性疾患
实验医学,31(6):减数分裂特异性粘连蛋白和染色体非整倍体疾病
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [石黒啓一郎, 渡邊嘉典]
通讯作者: 渡邊嘉典
43
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    • 批准号:
      20520521
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.33万
    • 财政年份:
      2008
    • 负责人:
      WATANABE Yoshinori
    • 依托单位:
    Optimization of waveguide components for symmetric-Mach-Zehnder-type all-optical switch based on photonic crystals
    • 批准号:
      18560030
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.11万
    • 财政年份:
      2006
    • 负责人:
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    • 依托单位:
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    • 批准号:
      14380324
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.6万
    • 财政年份:
      2002
    • 负责人:
      WATANABE Yoshinori
    • 依托单位:
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