Molecular mechanisms that determine kinetochore orientation acting at the heart of genome transition
Molecular mechanisms that determine kinetochore orientation acting at the heart of genome transition
批准号:
21000010
负责人:
WATANABE Yoshinori
金额:
$221.31万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Specially Promoted Research
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
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英文摘要
We have proven that cohesion at the core centromere defines mono-orientation of kinetochores. We show that chiasmata between homologous chromosomes ensure mono-orientation. We identified the kinase antagonizing shugoshin-PP2A. We further identified the inner centromere-shugoshin (ICS) network that is critical for chromosome segregation and the conserved regulatory mechanism of shaping chromosomes.
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发表时间:
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影响因子:
--
作者:
[]
通讯作者:
Tension across centromeres refines centromeric protection by shugoshin
着丝粒间的张力通过 shugoshin 改善着丝粒保护
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Watanabe, Y]
通讯作者:
Y
Aurora B mediated phosphorylation of hSgo2 is crucial for chromosome congression and centromeric protection
Aurora B 介导的 hSgo2 磷酸化对于染色体会聚和着丝粒保护至关重要
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Watanabe, Y]
通讯作者:
Y
実験医学,31(6):減数分裂特異的コヒーシンと染色体異数性疾患
实验医学,31(6):减数分裂特异性粘连蛋白和染色体非整倍体疾病
DOI:
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发表时间:
2013
期刊:
影响因子:
--
作者:
[石黒啓一郎, 渡邊嘉典]
通讯作者:
渡邊嘉典
2. 染色体分配の基本原理の解明(読売新聞 2013.3.21)
2. 阐明染色体分离的基本原理(读卖新闻 2013.3.21)
DOI:
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发表时间:
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作者:
[]
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共 43 条
Developing and validating the effectiveness and feasibility of training courses in English language teacher proficiency
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批准号:20520521
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2008
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负责人:WATANABE Yoshinori
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依托单位:
Optimization of waveguide components for symmetric-Mach-Zehnder-type all-optical switch based on photonic crystals
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批准号:18560030
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2006
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负责人:WATANABE Yoshinori
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依托单位:
Identifying the needs of the teachers of English as a Foreign Language and developing a pilot version of the teacher certification examination
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批准号:17520364
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2005
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负责人:WATANABE Yoshinori
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依托单位:
Analysis of the regulation of meiosis-specific chromosome segregation
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批准号:14380324
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
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财政年份:2002
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负责人:WATANABE Yoshinori
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依托单位:
Regulation of meiotic chromosome segregation by cohesin Rec8
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批准号:12480207
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.56万
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财政年份:2000
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负责人:WATANABE Yoshinori
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依托单位:
海外基金