In vivo whole-cell recording analysis of response properties of vestibular nucleus neuron to head rotation

利用全细胞记录技术研究了大鼠体内制剂中前庭内侧核神经元对头部旋转的反应特性。大多数MVN神经元在头部向记录侧旋转时，放电频率增加。此外，神经元表现出双组分的后超极化和相对恒定的脉冲间隔的重复放电模式。这一发现表明，显示出特定内在特性的MVN神经元对头部向特定方向旋转作出反应。

We investigated the response properties of neurons in the medial vestibular nucleus (MVN) to head rotations using whole-cell recordings in in vivo preparations of rats. Most MVN neurons tested increased the firing frequency in response to the head rotation to the recording side. Furthermore, the neurons showed an afterhyperpolarization with dual components and a repetitive firing pattern with relatively constant interspike intervals. This finding suggests that MVN neurons that show specific intrinsic properties respond to the head rotation to a specific direction.