In vivo whole-cell recording analysis of response properties of vestibular nucleus neuron to head rotation

我们研究了前庭内侧核（MVN）的神经元的响应特性，头部旋转使用全细胞记录在体内制备的大鼠。大多数测试的MVN神经元增加了响应于头部旋转到记录侧的放电频率。此外，神经元表现出后超极化与双组件和重复放电模式与相对恒定的峰间间期。这一发现表明，MVN神经元表现出特定的内在特性，响应头部旋转到特定的方向。

We investigated the response properties of neurons in the medial vestibular nucleus (MVN) to head rotations using whole-cell recordings in in vivo preparations of rats. Most MVN neurons tested increased the firing frequency in response to the head rotation to the recording side. Furthermore, the neurons showed an afterhyperpolarization with dual components and a repetitive firing pattern with relatively constant interspike intervals. This finding suggests that MVN neurons that show specific intrinsic properties respond to the head rotation to a specific direction.