In vivo whole-cell recording analysis of response properties of vestibular nucleus neuron to head rotation

我们在大鼠的活体标本中用全细胞记录的方法研究了前庭内侧核(MVN)神经元对头部旋转的反应特性。大多数被测试的MVN神经元增加了放电频率，以响应头部向记录侧旋转。此外，神经元表现出双成分的后超极化和相对恒定的间歇放电的重复放电模式。这一发现表明，表现出特定内在特性的MVN神经元对头部旋转到特定方向做出反应。

We investigated the response properties of neurons in the medial vestibular nucleus (MVN) to head rotations using whole-cell recordings in in vivo preparations of rats. Most MVN neurons tested increased the firing frequency in response to the head rotation to the recording side. Furthermore, the neurons showed an afterhyperpolarization with dual components and a repetitive firing pattern with relatively constant interspike intervals. This finding suggests that MVN neurons that show specific intrinsic properties respond to the head rotation to a specific direction.