Construction of Integrated Molecular Network Based on Interaction and Structural Information

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We have developed an integrated database/tool of biomolecular network, PDBnet, based on the structural and interaction information, in order to get useful information from the structurome. We have developed various interfaces for searching data and visualizing the results, which enables users to get insight into the relationship among structure, interaction, network and function of molecules. Using the data in PDBnet, we have made systematic analyses on the relationship among various properties at molecular structure, interaction and network levels to demonstrated the utility of PDBnet.