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Elucidation of structure-function of unique bacterial flagellar stator complex from Bacillus spp.

Elucidation of structure-function of unique bacterial flagellar stator complex from Bacillus spp.
阐明芽孢杆菌属独特细菌鞭毛定子复合物的结构功能。
批准号:
21370074
负责人:
ITO Masahiro
金额:
$9.57万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012

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中文摘要
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英文摘要
At first, we identified that the flagellar motor of B. subtilis was a hybrid motor and it rotated by using both ion motive forces, H+ and Na+, by a single molecular mechanism. Next, the critical charged amino acid residues between the second and third transmembrane cytoplasmic loop region in MotA and MotP subunits of B. subtilis were identified by using site-directed mutagenesis. Moreover, we identified a novel type flagellar motor from alkaliphilic Bacillus alcalophilus which stimulates swimming speed under elevated K+ or Rb+ concentrations. This is the first report that describes aflagellar motor that can use both K+ and Rb+ as coupling ions.
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发表时间: 2012
期刊:
影响因子: --
作者: [Yu Nakabayashi, Satoshi Kawashima, Kazuko Matsubara, Norihiko Sano, Takemi Enomoto, Kozo Tanaka, Masayuki Seki and Masami Horikoshi, Koyama K. and Ito M.]
通讯作者: Koyama K. and Ito M.
56
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