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Investigation on toxicity of 1-bromopropane to central nervous system and hematopoetic function in humans

Investigation on toxicity of 1-bromopropane to central nervous system and hematopoetic function in humans
1-溴丙烷对人体中枢神经系统和造血功能的毒性研究
批准号:
21406017
负责人:
ICHIHARA Gaku
金额:
$11.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
The analysis of workers exposed to 1-bromopropane and non-exposed workers was conducted using ANOVA followed by Dunnett's multiple comparison and regression analysis. The result showed dose-dependent increase in distal latency, threshold for vibration sense, LDH, TSH, FSH and dose-dependent decrease in sensory nerve conduction velocity, red blood cell, hematocrit. The cases intoxicated with 1-bromopropane showed degeneration of peripheral nerve histopathologically and the abnormality in the central nervous system.
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会议论文
Comparative study on susceptibility to 1-bromopropane in three mice strains.
三种品系小鼠对1-溴丙烷敏感性的比较研究。
DOI: --
发表时间: 2009
期刊: Toxicol Sci 112(1)
影响因子: --
作者: [Liu F, Ichiharhar S, Mohideen SS, Sai U, Kitoh J, Ichihara G.]
通讯作者: Ichihara G.
Central nerve system toxicity of 1-bromopropane: an oxidative stress hypothesis.
1-溴丙烷的中枢神经系统毒性:氧化应激假说。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [原田久美, 小川智子, 角大悟, 姫野誠一郎., Subramanian K.]
通讯作者: Subramanian K.
Pleural plaques profile on chest radiograph and CT scan of asbestos-exposed Japanese construction workers.
接触石棉的日本建筑工人的胸片和 CT 扫描中的胸膜斑块轮廓。
DOI: --
发表时间: 2011
期刊: Ind Health
影响因子: 2
作者: [Sahabudeen Sheik Mohideen, Sahoko Ichihara, Zhenlie Huang, Lingyi Zhang, Kaviarasan Suburamanian, Gaku Ichihara., Elshazley M.]
通讯作者: Elshazley M.
酒井潔建設作業者の職種と胸膜肥厚斑発生部位に関する検討
酒井清建筑工人职业及胸膜增厚斑块发生部位研究
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [柴田英治, Mo' men Hafez, 市原学, 市原佐保子, 上島通浩]
通讯作者: 上島通浩
87
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