Investigation on toxicity of 1-bromopropane to central nervous system and hematopoetic function in humans
Investigation on toxicity of 1-bromopropane to central nervous system and hematopoetic function in humans
批准号:
21406017
负责人:
ICHIHARA Gaku
金额:
$11.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The analysis of workers exposed to 1-bromopropane and non-exposed workers was conducted using ANOVA followed by Dunnett's multiple comparison and regression analysis. The result showed dose-dependent increase in distal latency, threshold for vibration sense, LDH, TSH, FSH and dose-dependent decrease in sensory nerve conduction velocity, red blood cell, hematocrit. The cases intoxicated with 1-bromopropane showed degeneration of peripheral nerve histopathologically and the abnormality in the central nervous system.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Comparative study on susceptibility to 1-bromopropane in three mice strains.
三种品系小鼠对1-溴丙烷敏感性的比较研究。
DOI:
--
发表时间:
2009
期刊:
Toxicol Sci 112(1)
影响因子:
--
作者:
[Liu F, Ichiharhar S, Mohideen SS, Sai U, Kitoh J, Ichihara G.]
通讯作者:
Ichihara G.
Central nerve system toxicity of 1-bromopropane: an oxidative stress hypothesis.
1-溴丙烷的中枢神经系统毒性:氧化应激假说。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[原田久美, 小川智子, 角大悟, 姫野誠一郎., Subramanian K.]
通讯作者:
Subramanian K.
Pleural plaques profile on chest radiograph and CT scan of asbestos-exposed Japanese construction workers.
接触石棉的日本建筑工人的胸片和 CT 扫描中的胸膜斑块轮廓。
DOI:
--
发表时间:
2011
期刊:
Ind Health
影响因子:
2
作者:
[Sahabudeen Sheik Mohideen, Sahoko Ichihara, Zhenlie Huang, Lingyi Zhang, Kaviarasan Suburamanian, Gaku Ichihara., Elshazley M.]
通讯作者:
Elshazley M.
酒井潔建設作業者の職種と胸膜肥厚斑発生部位に関する検討
酒井清建筑工人职业及胸膜增厚斑块发生部位研究
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[柴田英治, Mo' men Hafez, 市原学, 市原佐保子, 上島通浩]
通讯作者:
上島通浩
DOI:
--
发表时间:
2009
期刊:
Toxicol
影响因子:
--
作者:
[Huang F, Ning H, Xin QQ, Huang Y, Wang H, Zhang ZH, Xu DX, Ichihara G]
通讯作者:
Ichihara G
共 87 条
Investigation on neurodegenerative effect of 1-bromopropane using new biomarkers
-
批准号:24406018
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2012
-
负责人:ICHIHARA Gaku
-
依托单位:
Role of neurogenesis in mechanism of chronic or late-onset toxicity of environmental chemicals to the central nervous system
-
批准号:23659326
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:ICHIHARA Gaku
-
依托单位:
Study on oxidative stress and glial activation explaining demyelination in the central nervous system induced by alternative to freons
-
批准号:22390120
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.56万
-
财政年份:2010
-
负责人:ICHIHARA Gaku
-
依托单位:
Analysis of molecular and cellular targets in neurotoxicity of alternatives to ozone-depleting substances and establishment of biomarkers for the central nervous toxicity
-
批准号:19390160
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.15万
-
财政年份:2007
-
负责人:ICHIHARA Gaku
-
依托单位:
Study on dose-dependency of the central nervous system toxicity of 1-bromopropane in humans
-
批准号:17406017
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.77万
-
财政年份:2005
-
负责人:ICHIHARA Gaku
-
依托单位:
Investigation on protein adduct produced by alternatives to ozone-depleting substances and susceptibility genes and establishment of new method for risk assessment.
-
批准号:16390169
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.6万
-
财政年份:2004
-
负责人:ICHIHARA Gaku
-
依托单位:
Investigation on neurologic abnormality induced by 1-bromoproane and individual variation in susceptibility
-
批准号:14406015
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2002
-
负责人:ICHIHARA Gaku
-
依托单位:
INVESTIGATION ON TOXICITIES OF ALTERNATIVES FOR CHLOROFLUOROCARBONS AND ITS RISK ASSESSMENT USING MOLECULAR AND BIOLOGICAL MARKERS.
-
批准号:13470088
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2001
-
负责人:ICHIHARA Gaku
-
依托单位:
Development Deregulating system for inhalation exposure to volatile organic chemicals (VOCs) for toxicity testing
-
批准号:12557039
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.62万
-
财政年份:2000
-
负责人:ICHIHARA Gaku
-
依托单位:
Study on mechanism of reproductive toxicity and neurotoxicity of 1-bromopropane, a new alternative to chlorofluorocarbons
-
批准号:11670367
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.5万
-
财政年份:1999
-
负责人:ICHIHARA Gaku
-
依托单位:
海外基金