Development of innovative multimodal imaging probes using organosilica particle technology

在这项研究中，我们利用有机二氧化硅颗粒技术开发了新型成像探针。我们制备了各种成像探针，它们可用于体外和体内荧光成像、x射线计算机断层扫描（CT）、磁共振成像（MRI）等。此外，我们还开发了用于成像的多模态成像探针，结合了荧光成像，x射线CT和MRI。该成像探针可用于小鼠肿瘤组织的体内检测等多种应用。成功开发了用于生物医学研究的创新型多模态成像探针。

In this study, we developed novel imaging probes using organosilica particle technology. We prepared various kinds of imaging probes, and they were useful for in vitro and in vivo fluorescent imaging, X-ray computed tomography(CT), magnetic resonance imaging(MRI) and so on. Furthermore we also developed multimodal imaging probes for imaging that combine fluorescent imaging, X-ray CT, and MRI. The imaging probes were useful for various applications such as in vivo detections of tumor tissue of mouse. Useful innovative multimodal imaging probes for biomedical studies were developed successfully.