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Regulation of blood pressure by secreted adipocyte-derived leucine aminopeptidase

Regulation of blood pressure by secreted adipocyte-derived leucine aminopeptidase
分泌的脂肪细胞来源的亮氨酸氨基肽酶调节血压
批准号:
21780103
负责人:
GOTO Yoshikuni
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
Adipocyte-derived leucine amnopeptidase (A-LAP) may play role in the blood pressure regulation. In this study, it is revealed that ER-retained A-LAP is secreted from macrophages in response to activation by treatment with lipopolysaccharide and interferon-γ, and supply of arginine for nitric oxide synthesis from peptide to cells. These results suggest that secretion of A-LAP is important for hypertensive action.
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DOI: --
发表时间: 2011
期刊: Journal of Immunology
影响因子: 4.4
作者: [Takeshi Ikeda, Kei Motomura, Yuuya Agou, Takenori Ishida, Ryuichi Hirota, Akio Kuroda, Irini Evnouchidou]
通讯作者: Irini Evnouchidou
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [池田丈, 本村圭, 吾郷友哉, 廣田隆一, 黒田章夫, 後藤芳邦]
通讯作者: 後藤芳邦
DOI: 10.1074/jbc.m111.239111
发表时间: 2011-06-17
期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子: 4.8
作者: [Goto, Yoshikuni, Ogawa, Kenji, Tsujimoto, Masafumi]
通讯作者: Tsujimoto, Masafumi
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Ito S, Kawamura H, Niwa Y, Nakamichi N, Yamashino T, Mizuno T, 後藤芳邦]
通讯作者: 後藤芳邦
8
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    • 批准号:
      19K07405
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2019
    • 负责人:
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    • 资助金额:
      $3.16万
    • 财政年份:
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    • 负责人:
      GOTO Yoshikuni
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    • 批准号:
      24790083
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.83万
    • 财政年份:
      2012
    • 负责人:
      GOTO Yoshikuni
    • 依托单位:
    海外基金