Elucidation of drug resistance mechanism indicated by DNA methylation in colon cancer
Elucidation of drug resistance mechanism indicated by DNA methylation in colon cancer
批准号:
21790140
负责人:
SUZUKI Hideo
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
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英文摘要
(1)The SNP of EGFR D944D in Exon25 was statistically correlated with the expression of skin toxicity in unresectable colorectal cancer patients administrated anti-EGFR antibody, suggesting that application to personalized medication that enables the prediction of this side effect.(2)By comprehensive analysis of DNA methylation in gastric washes before and after endoscopic treatment, methylation in MINT25 and SOX17 gene was reduced significantlyafter treatment with curative resection in early gastric cancer patients. This method may be useful for early detection of recurrence after endoscopic treatment.
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胃粘膜洗浄液を利用した疾患関連マーカー検出方法
利用胃粘膜灌洗液检测疾病相关标志物的方法
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[]
通讯作者:
The Sox17 Gene Hypermethylation is Useful as a Molecular Diagnostic Application in Early Stage of Gastric Cancer.
Sox17 基因高甲基化可作为胃癌早期的分子诊断应用。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hama R, Watanabe Y et al.]
通讯作者:
Watanabe Y et al.
胃洗浄廃液を用いた胃がんメチル化マーカーの探索
利用洗胃废液寻找胃癌甲基化标志物
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Iwayanagi Y, et al., 渡邊嘉行]
通讯作者:
渡邊嘉行
消化器内視鏡検査と分子生物学的診断の新たな展開
胃肠内镜及分子生物学诊断新进展
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[細谷浩介, 渡邊嘉行]
通讯作者:
渡邊嘉行
エピジェネティックと大腸癌
表观遗传学和结直肠癌
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hiroshi Suzuki, Takashi Yoshikado, Takehito Yamamoto, Hiroko Yamaji, Kousei Ito, Tappei Takada, 渡邊嘉行]
通讯作者:
渡邊嘉行
共 8 条
An advanced model for evaluating service quality and customer satisfaction
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批准号:23310105
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.9万
-
财政年份:2011
-
负责人:SUZUKI Hideo
-
依托单位:
Indices of Service Quality, Customer Satisfaction and Loyalty in Japanese Service Industries
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批准号:20510125
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.58万
-
财政年份:2008
-
负责人:SUZUKI Hideo
-
依托单位:
A Study of English Language Education within Liberal Arts Context at The Japanese Universities in the 21^<st> Century
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批准号:14201052
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$28.37万
-
财政年份:2002
-
负责人:SUZUKI Hideo
-
依托单位:
How To Construct E-Text Archives and How To Apply them to Cultural Studies
-
批准号:10410102
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.94万
-
财政年份:1998
-
负责人:SUZUKI Hideo
-
依托单位:
Study of Extension for Forming Limit of Sheet Metal at High Temperature
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批准号:03650551
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1991
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负责人:SUZUKI Hideo
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依托单位:
Purification of a novel enzyme, 5'-nucleotide phosphodiesterase, and studies on its physiological role and relation to tumor.
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批准号:63571034
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1988
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负责人:SUZUKI Hideo
-
依托单位:
海外基金