Expression analysis of SFRP family genes for development of molecular targeted therapy for oral cancer
Expression analysis of SFRP family genes for development of molecular targeted therapy for oral cancer
SFRP家族基因表达分析用于口腔癌分子靶向治疗的开发
批准号：
21792021
负责人：
SOGABE Yohei
金额：
$2.75万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
项目状态：
已结题
起止时间：
2009 至 2010
中文摘要
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英文摘要
In the present study, we examined the relationship between Wnt signaling and epigenetic alteration of the secreted frizzled-related protein (SFRP) genes in OSCC. Our results confirm the frequent methylation and silencing of SFRP genes in OSCC, and suggest that their loss of function contributes to activation of Wnt signaling that leads to cell proliferation during oral carcinogenesis.
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Expression analysis of DKK gene and development of a molecular targeted therapy for oral cancer
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批准号：23792365
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项目类别：Grant-in-Aid for Young Scientists (B)
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资助金额：$2.66万
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财政年份：2011
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负责人：SOGABE Yohei
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依托单位：
海外基金
