Research to clarify the relationship between brain function and swallowing in patients with anterior open bite using functional MRI

结果表明，前牙开牙合患者下颌前磨牙突出，下颌向后、向下旋转，覆牙合增多，覆盖减少。在功能上，错牙合时的咬合力和咬合面积明显较小，下颌运动时髁突的运动受限。FMRI研究结果显示，PCC和VTA呈现阳性的自我面孔特异性激活。PCC可能起到将积极自我面孔加工为自身特质和从积极的自传体记忆中提取积极自我形象的作用。PCC的激活程度可能与自我概念有关。同时，VTA作为奖励系统的一部分，可能会将积极的自我面子处理为社会奖励。LSE中VTA的激活受对比效应的调节，可能反映了其对自身负反馈的耐受性较低。这些结果表明，PCC和VTA与积极的自我面子评价有关，而自我面子评价与自尊在神经水平上存在联系。

We elucidated that the patients with anterior open bite have extruded lower molars and rotated mandible backward and downward, and increased Overjet and decreased Overbite in morphologic findings. In funcition, they have significantly small occlusal force and occlusal area during intercuspation, and limited condylar motion during jaw movements. As the result of fMRI study, PCC and VTA showed positive self-face specific activation. PCC might play the role of processing of positive self-face as one's own traits and retrieving positive self-image from positive autobiographical memory. The degree of PCC activation might be related to one's self-concept. Meanwhile, VTA, which is the part of the reward system, might process positive self-face as social reward. VTA activation modulated by contrast effect in LSEs might reflect the lower tolerability for one's own negative feedback. These results suggest that PCC and VTA are related to positive self-face evaluation, and self-face evaluation links with self-esteem at the neural level.