Research to clarify the relationship between brain function and swallowing in patients with anterior open bite using functional MRI

使用功能性 MRI 阐明前牙开牙合患者脑功能与吞咽之间关系的研究

• 批准号: 21792055
• 负责人: HASHIMOTO Takashi
• 金额: $ 2.25万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21792055/
• 关键词: 前歯部開咬; 異常嚥下運動; 脳機能

We elucidated that the patients with anterior open bite have extruded lower molars and rotated mandible backward and downward, and increased Overjet and decreased Overbite in morphologic findings. In funcition, they have significantly small occlusal force and occlusal area during intercuspation, and limited condylar motion during jaw movements. As the result of fMRI study, PCC and VTA showed positive self-face specific activation. PCC might play the role of processing of positive self-face as one's own traits and retrieving positive self-image from positive autobiographical memory. The degree of PCC activation might be related to one's self-concept. Meanwhile, VTA, which is the part of the reward system, might process positive self-face as social reward. VTA activation modulated by contrast effect in LSEs might reflect the lower tolerability for one's own negative feedback. These results suggest that PCC and VTA are related to positive self-face evaluation, and self-face evaluation links with self-esteem at the neural level.

我们发现，前牙开合患者的下磨牙突出，下颌骨向后和向下旋转，在形态学上表现为Overjet增加和Overbite减少。在功能上，它们在咬合时咬合力和咬合面积明显小，下颌运动时髁突运动受限。fMRI结果显示，PCC和VTA呈阳性的自我面孔特异性激活。PCC可能发挥了积极自我面孔作为自身特征加工和积极自传体记忆提取积极自我形象的作用。PCC的激活程度可能与自我概念有关。同时，VTA作为奖励系统的一部分，可能将积极的自我面孔加工为社会奖励。lse中由对比效应调节的VTA激活可能反映了个体对自身负反馈的耐受性较低。这些结果表明，PCC和VTA与积极的自我面子评价有关，而自我面子评价与自尊在神经水平上存在联系。

项目成果

Mandibular deviation and canted maxillary occlusal plane treated with miniscrews and intraoral vertical ramus osteotomy: Functional and morphologic changes

• DOI: 10.1016/j.ajodo.2007.06.022
• 发表时间: 2009-12-01
• 期刊: AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
• 影响因子: 3
• 作者: Hashimoto, Takashi;Fukunaga, Tomohiro;Takano-Yamamoto, Teruko
• 通讯作者: Takano-Yamamoto, Teruko

自己顔評価と自尊感情:Contrast effectを用いたfMRI研究

自我面孔评估和自尊：使用对比效应的功能磁共振成像研究

• 发表时间: 2010
• 作者: 及川拓;橋本隆志
• 通讯作者: 橋本隆志

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