Research to clarify the relationship between brain function and swallowing in patients with anterior open bite using functional MRI

使用功能性 MRI 阐明前牙开牙合患者脑功能与吞咽之间关系的研究

• 批准号: 21792055
• 负责人: HASHIMOTO Takashi
• 金额: $ 2.25万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21792055/
• 关键词: 前歯部開咬; 異常嚥下運動; 脳機能

We elucidated that the patients with anterior open bite have extruded lower molars and rotated mandible backward and downward, and increased Overjet and decreased Overbite in morphologic findings. In funcition, they have significantly small occlusal force and occlusal area during intercuspation, and limited condylar motion during jaw movements. As the result of fMRI study, PCC and VTA showed positive self-face specific activation. PCC might play the role of processing of positive self-face as one's own traits and retrieving positive self-image from positive autobiographical memory. The degree of PCC activation might be related to one's self-concept. Meanwhile, VTA, which is the part of the reward system, might process positive self-face as social reward. VTA activation modulated by contrast effect in LSEs might reflect the lower tolerability for one's own negative feedback. These results suggest that PCC and VTA are related to positive self-face evaluation, and self-face evaluation links with self-esteem at the neural level.

我们阐明，前牙开牙合患者的下磨牙突出，下颌骨向后和向下旋转，并且在形态学表现上覆咬合增加，覆咬合减少。在功能上，它们在牙尖交错期间具有明显较小的咬合力和咬合面积，并且在下颌运动期间髁突运动有限。 fMRI 研究结果显示，PCC 和 VTA 表现出积极的自我面部特异性激活。 PCC可能起到将积极的自我面貌加工为自身特征并从积极的自传体记忆中检索积极的自我形象的作用。 PCC激活的程度可能与一个人的自我概念有关。同时，VTA作为奖励系统的一部分，可能会将积极的自我面子处理为社会奖励。 LSE 中对比效应调节的 VTA 激活可能反映了个体对自身负反馈的较低耐受性。这些结果表明PCC和VTA与积极的自我面子评价有关，而自我面子评价在神经水平上与自尊有联系。

项目成果

Mandibular deviation and canted maxillary occlusal plane treated with miniscrews and intraoral vertical ramus osteotomy: Functional and morphologic changes

• DOI: 10.1016/j.ajodo.2007.06.022
• 发表时间: 2009-12-01
• 期刊: AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
• 影响因子: 3
• 作者: Hashimoto, Takashi;Fukunaga, Tomohiro;Takano-Yamamoto, Teruko
• 通讯作者: Takano-Yamamoto, Teruko

自己顔評価と自尊感情:Contrast effectを用いたfMRI研究

自我面孔评估和自尊：使用对比效应的功能磁共振成像研究

• 发表时间: 2010
• 作者: 及川拓;橋本隆志
• 通讯作者: 橋本隆志

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