Research to clarify the relationship between brain function and swallowing in patients with anterior open bite using functional MRI

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We elucidated that the patients with anterior open bite have extruded lower molars and rotated mandible backward and downward, and increased Overjet and decreased Overbite in morphologic findings. In funcition, they have significantly small occlusal force and occlusal area during intercuspation, and limited condylar motion during jaw movements. As the result of fMRI study, PCC and VTA showed positive self-face specific activation. PCC might play the role of processing of positive self-face as one's own traits and retrieving positive self-image from positive autobiographical memory. The degree of PCC activation might be related to one's self-concept. Meanwhile, VTA, which is the part of the reward system, might process positive self-face as social reward. VTA activation modulated by contrast effect in LSEs might reflect the lower tolerability for one's own negative feedback. These results suggest that PCC and VTA are related to positive self-face evaluation, and self-face evaluation links with self-esteem at the neural level.