An experimental study for a novel gene therapy for the highly malignant tumor of salivary gland using nanobubbles and ultrasound

本研究的目的是利用纳米气泡和超声技术开发一种新的涎腺高度恶性肿瘤的诊断和基因治疗系统。在本研究中，我们利用实验性肿瘤模型，利用纳米气泡和高频超声图像分析设备，开发了一套高分辨率诊断成像系统。此外，我们还提出了一种新的基因治疗方法的可能性，通过转移抑制肿瘤生长的质粒DNA，利用纳米气泡和超声波。

The aim of the present study is to develop a novel diagnosis and gene therapy system for the highly malignant tumor of salivary gland using nanobubbles and ultrasound. In the present study, by using experimental tumor model, we developed a high-resolution diagnostic imaging system utilizing nanobubbles and high-frequency ultrasound image analysis equipment. In addition, we were able to present the possibility of a new gene therapy method by transfer of a plasmid DNA, which inhibited the tumor growth, by utilizing nanobubbles and ultrasound.