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Epidemiological study of dry mouth in the elderly -etiology, progress, treatment, recuperation-

老年人口干的流行病学研究-病因、进展、治疗、调理-

基本信息

批准号：
07670421
负责人：
SAKAMOTO Maya
金额：
$ 0.58万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670421/
关键词：
Dry mouth Xerostomia Elderly Medication side effect Epidemiologic Study Xerostomia

项目摘要

Dry mouth caused by salivary gland hypofunction is a common disoder in elderly persons. However, there have been no surveys reported of dry mouth of the elderly in Japan. The purpose of this study was to evaluate the prevalence and causes of dry mouth in the elderly. The subjects of the study were 95 elderly persons (men m=31, women n=64), aged 65 to 96 years (mean=78) in 3 homes for senior citizens. We asked them detailed questions about various symptoms related to dry mouth, using a specially designed questionnaire. Then we examined missing tooth, oral mucosal lesions and salivary flow-rate by gum test. The results were as follows :1. Twenty-three (24.2%) of the subjects noticed subjective sensation of dry mouth. 2. The gum test demonstrated decreased saliva secretion in 48.3% of 89 persons. Severe decreased salivation was observed only in 4 persons (4.5). 3. Out of the 95 subjects, 85 (89.5%) had at least one chronic systemic disease and 62 (65.3%) were taking at least one xerostomic medication, (e, g., antihypertensive drugs, antihistemics, anticholinergic drugs, antidepressants, psychotropic drugs, antiparkinsonian medication, and diuretics). 4. Those who taking three kinds of xerostomic medication were found to have significantly diminished salivation or sensation of dry mouth. 5. Atrophic change of tongue (22.1%), lobulated tongue (24.2%) and angular cheilitis (2.1%) were clinically observed. No disease of the oral mucosa, such as Leukoplakia, Candidiasis, Oral lichen planus or Aphthous ulcers, were observed.

唾液腺功能减退引起的口干是老年人的常见疾病。然而，在日本还没有关于老年人口干的调查报告。本研究的目的是评估老年人口干的患病率和原因。研究对象为95名老年人（男性m=31，女性n=64），年龄为65至96岁（平均=78），在3个老人院。我们使用专门设计的问卷，向他们详细询问了与口干有关的各种症状。然后通过牙龈试验检查缺失牙、口腔粘膜病变和唾液流率。结果如下：1. 23例（24.2%）受试者注意到口干的主观感觉。2.牙龈测试显示89人中有48.3%的人唾液分泌减少。仅在4例患者中观察到严重流涎减少（4.5）。3.在95名受试者中，85名（89.5%）患有至少一种慢性全身性疾病，62名（65.3%）正在服用至少一种口腔干燥药物（例如，抗高血压药、抗组织血药、抗胆碱能药、抗抑郁药、精神药物、抗帕金森病药和利尿剂）。4.那些服用三种口腔干燥药物的人被发现唾液分泌或口干感显着减少。5.临床表现为舌萎缩（22.1%）、分叶状舌（24.2%）和口角炎（2.1%）。未观察到口腔粘膜疾病，如白斑病、念珠菌病、口腔扁平苔藓或口疮性溃疡。