Studies on relationship between structure and antifungal activity of plant chitinases with aid of diversity of genes from subtropical plants.

在这项研究中，我们借助亚热带植物基因的多样性，研究了植物几丁质酶的结构与其抗真菌活性之间的关系。为了明确几丁质酶的电荷和抗真菌活性之间的关系，我们进行了突变分析。具有较高正电荷的突变体具有较高的抗真菌活性。这些发现将有助于开发安全有效的农业和医药抗真菌药物。

In this study, we examined relationship between structures of plant chitinases and their antifungal activities with aid of diversity of genes from subtropical plants. To clear relationship between charge and antifungal activity of chitinases, mutational analyses were done. Mutants having higher positive charge exhibited higher antifungal activity. These findings would contribute to development of safe and effective antifungal agents for agriculture and medicine.