Bioengineering of artificial red cells for clinical application
Bioengineering of artificial red cells for clinical application
批准号:
22300161
负责人:
SAKAI Hiromi
金额:
$11.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
One of the characteristics of artificial red cells (hemoglobin-vesicles) as a molecular assembly is that their physicochemical properties can be manipulated. New function can also be added to the particles. In this reasech we take the advantages of such artificial red cells to apply for new clinical indications which blood transfusion cannot be attained. We establish “gas bioengineering” using artificial red cells.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Repeated injection of high dose of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.
重复注射高剂量的血红蛋白封装脂质体(血红蛋白囊泡)可在失血性休克大鼠模型中诱导加速血液清除。
DOI:
--
发表时间:
2011
期刊:
Drug Metab. Dispos
影响因子:
--
作者:
[K. Taguchi, Y. Iwao, H. Watanabe, D. Kadowaki, H. Sakai, K. Kobayashi, H. Horinouchi, T. Maruyama, M. Otagiri]
通讯作者:
M. Otagiri
Gas Bioengineering of Artificial Red Cells (invited)
人工红细胞气体生物工程(特邀)
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Edgar Yuji Egawa, Koichi Kato, Makiko Hiraoka, Tadashi Nakaji-Hirabayashi, Hiroo Iwata, 柳沢大治郎, H. Sakai]
通讯作者:
H. Sakai
Cardiopulmonary hemodynamic responses to the injection of hemoglobin-vesicles (artificial oxygen carriers) in miniature pigs
小型猪注射血红蛋白囊泡(人工氧载体)的心肺血流动力学反应
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[H. Sakai, Y. Suzuki, K. Sou, M. Kano]
通讯作者:
M. Kano
Intravenous injection of Hb-vesicles (artificial oxygen carriers) after hemodilution with a series of plasma expanders (water-soluble biopolymers) in a rat repeated hemorrhage model.
在大鼠反复出血模型中,用一系列血浆扩张剂(水溶性生物聚合物)进行血液稀释后,静脉注射 Hb 囊泡(人工氧载体)。
DOI:
--
发表时间:
2011
期刊:
Polymers Adv. Technol.
影响因子:
--
作者:
[H. Sakai, N. Miyagawa, H. Horinouchi, S. Takeoka, M. Takaori, E. Tsuchida, K. Kobayashi]
通讯作者:
K. Kobayashi
NHK E テレ「サイエンスZERO」人工赤血球の研究を紹介(2012年7月15日) 報道等
NHK E-TV《Science ZERO》介绍人工红细胞的研究(2012年7月15日)报道等
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 66 条
Development of a portable training equipment for hemiplegic upper extremity
-
批准号:15K12711
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$1.58万
-
财政年份:2015
-
负责人:SAKAI Hiromi
-
依托单位:
Microhemodynamic properties and gas reactions of abnormal RBCs in narrow tubes
-
批准号:24650301
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2012
-
负责人:SAKAI Hiromi
-
依托单位:
A study of Korean Diplomacy to Japan from 1876 to 1894
-
批准号:21820014
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.68万
-
财政年份:2009
-
负责人:SAKAI Hiromi
-
依托单位:
Artificial Red Cells : Physiological Importance of the Ligand Reaction Dynamism and the New Application for Ligand Therapy
-
批准号:19300164
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.31万
-
财政年份:2007
-
负责人:SAKAI Hiromi
-
依托单位:
"Analysis of oxygen releasing behavior of hemoglobin-vesicles (nano-particles) and the mechanism of oxygenation of ischemic tissue."
-
批准号:16300162
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.54万
-
财政年份:2004
-
负责人:SAKAI Hiromi
-
依托单位:
Microhemodynamics after Infusion of an Artificial O_2 Carriers Using Laser Flash Irradiation.
-
批准号:12480268
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.47万
-
财政年份:2000
-
负责人:SAKAI Hiromi
-
依托单位:
海外基金