Mechanisms of genetic and environmental control of gonadal sex differentiation and reproductive function in fish

鱼类性腺性别分化和生殖功能的遗传和环境控制机制

• 批准号: 22380109
• 负责人: STRUSSMANN C.a.
• 金额: $ 9.57万
• 依托单位: Tokyo University of Marine Science and Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22380109/
• 关键词: 環境; 温度; 魚類; 遺伝; 生殖; 性分化; 性決定; ストレス; 生理

This study examined how water temperature modulates the expression dynamics of several genes related to gonadal sex differentiation and reproductive function of fish, the process and effects of heat-induced gonadal apoptosis, the process and effects of environment-induced stress on gonadal sex determination, and the roles of the central nervous system in temperature-dependent gonadal sex determination using medaka and atheriniform fishes as models. This study provides novel and crucial insights on the molecular, biochemical, and physiological pathways of action of water temperature on the processes of gonadal sex differentiation and reproductive function of fish.

本研究以青鳉和银汉鱼为模型，探讨了水温对鱼类性腺性别分化和生殖功能相关基因表达的影响、热诱导性腺凋亡的过程和影响、环境胁迫对性腺性别决定的影响以及中枢神经系统在温度依赖性性腺性别决定中的作用。该研究为水温对鱼类性腺性别分化和生殖功能的分子、生化和生理作用途径提供了新的和重要的见解。

项目成果

Use of otolith microchemistry in the field assessment of the effects of water temperature on fish sex determination

利用耳石微化学现场评估水温对鱼类性别决定的影响

• 发表时间: 2010
• 作者: C.A.Strussmann;T.Oikawa;T.Otake
• 通讯作者: T.Otake

Molecular cloning and expression analysis of Fshr and Lhr in relation to Fshb and Lhb subunits during the period of temperature-dependent sex determination in pejerrey Odontesthes bonariensis

波纳里齿牙温度依赖性性别决定过程中Fshr和Lhr与Fshb和Lhb亚基的分子克隆及表达分析

• DOI: 10.1002/mrd.21179
• 发表时间: 2010
• 期刊: Molecular Reproduction and Development
• 影响因子: 2.5
• 作者: T. Shinoda;L.A. Miranda;K. Okuma;R.S.Hattori;J.I. Fernandino;G. Yoshizaki;G.M. Somoza;and C.A. Strussmann
• 通讯作者: and C.A. Strussmann

Implications of climate change for the reproductive capacity and survival of Atherinopsid fish species

气候变化对斑马鱼繁殖能力和生存的影响

• 发表时间: 2010
• 期刊: Journal of Fish Biology
• 影响因子: 2
• 作者: C.A. Strussmann;D.O. Conover;G.M. Somoza;and L.A. Miranda
• 通讯作者: and L.A. Miranda

High temperature inhibits cyp19a1a expression and estradiol synthesis in pejerrey (Odontesthes bonariensis) ovaries in vitro

高温抑制 Pejerrey (Odontesthes bonariensis) 卵巢中 cyp19a1a 表达和雌二醇合成

• 发表时间: 2012
• 作者: L.A. Miranda;M. Elisio;and C.A. Strussmann
• 通讯作者: and C.A. Strussmann

Molecular, endocrine, and environmental mechanisms of gonadal sex differentiation in fish and application for sex control

鱼类性腺性别分化的分子、内分泌和环境机制及其在性别控制中的应用

• 发表时间: 2011
• 作者: 北田修一(帰山雅 秀;永田光博;中川大介編);C.A. Strussmann
• 通讯作者: C.A. Strussmann