Endocrine and metabolic studies on single nucleotide polymorphism of GH gene in Japanese Black cattle

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1) We successfully established an applied method of Dot-plot-SNP for analyzing GH single nucleotide polymorphisms (SNPs), 2) In the studies on gene expression of fatty acid synthesis enzymes (FASN, SCD and SREBP-1), adipocytes isolated from the animal with type CC demonstrated greater sensitivity to GH stimulation than those with another type, 3) Glucose-clamp analysis demonstrated greater insulin sensitivity in the animals with the type AA than that with type BB.