A pharmacist's strategic practical use in promotion of gene medical treatment

为了促进针对个体基因差异的医学治疗，推进基因信息的医学研究，广泛推广基因筛查疗法是非常重要的。因此，在本研究中，清楚地表明记忆体重或心力衰竭对华法林的维持剂量有很大的影响，在反流性食管炎的治疗中，PPI的药物治疗受到了CYP2C19基因多态性的影响。此外，还成立了日本基因组药理学研究小组，以传播基因信息的相关知识和实际使用方法，并向神户的药剂师、医生、护士和市民举办了报告会。

For promotion of the medical treatment tailored to individual gene differences, it is important to advance the medical research on gene information and widely spread the genetic-screening therapy. So, in this research, it was shown clearly that the anamnestic weight or heart failure has big influence on a maintenance given dose of warfarin, and that in the reflux esophagitis therapy, the medical treatment with PPI has been affected by the gene polymorphism of CYP2C19. Furthermore, the Japanese genome pharmacology study group was established for the purpose of spreading the pertinent knowledge and the practical use method of gene information, andthe lecture meeting was held to the pharmacist, physician, nurse and the citizens of Kobe.