Control of Reaching by Remapping Visual Space Maps in the Frontal Eye Field

当一个球员伸手去打网球时，球员会做出协调的眼睛和手的运动来准确地击球，然后想象出伸手动作的结果。我们研究了猴子在只用眼睛、只用一只手或用眼睛和一只手一起去抓目标时弓状周皮层的神经元活动。弓状周皮层的分区在不同效应器的启动和执行中发挥不同的作用。特别是，深层皮层区域包含的神经元在达到执行之前和期间或在达到运动的自我监测期间都是恒定活跃的，无论眼睛、手或两者都用于达到。神经元活动的性质表明，弓周皮层从开始到结束都在协调到达动作，因此可以作为使用任何效应器的到达行为的使命控制。

When a player reaches for and hits a tennis ball, the player makes coordinated eye and hand movements to hit the ball accurately and subsequently visualize the outcome of the reaching action. We examined the neuronal activity in the periarcuate cortex of monkeys while using their eyes only, one hand only, or eyes and one hand together to reach for a target. Divisions of the periarcuate cortex play differential roles in the initiation and execution of reaching by the different effectors. In particular, the deep cortical region contained neurons that were invariantly active before and during reaching execution or during self-monitoring of the reaching movements regardless of whether the eyes, a hand, or both were used for reaching. The properties of the neuronal activities suggest that the periarcuate cortex orchestrates reaching movements from start to finish, thus serving as mission control for reaching behavior using any effector.