Dynamic Analysis of Information Processing in Brain for Reaching Movements

大脑信息处理的动态分析

• 批准号: 08680878
• 负责人: KURATA Kiyoshi
• 金额: $ 1.6万
• 依托单位: HIROSAKI UNIVERSITY (1997)Tohoku University (1996)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08680878/
• 关键词: Cerebral cortex; Premotor cortex; Sensorimotor integration; Visual coordinates; Motor coodinates; Transformation of coordinates; 視覚空間座標; 運動関連活動

The ventral premotor cortex (PMv)' of monkeys has been assumed to exert bilateral control over arm movements. However, it has been suggested recently that the PMv is the site where spatial visual inputs are transformed to moter commands. Then, an apperent relation to bilateral arm movements may be regarded as a neural process closer to the inputs from both visual hemifields. On the other hand, if neural processing is closer to the final motor commands, neuronal activity is expected to be more closely related to contralateral arm movements. To examine these possibilities, in the presence of shift prisms that dissociated visual from motor space, two monkeys were trained to reach a visually presented target by either their right or left arm. Before target presentation, auditory cues instructed which arm should be used for the task. Three types of movement-related activities were recorded in PMv : the first reflected visual, but not motor, space (V neurons) ; the second reflected motor, but not visual, space (M neurons) ; and the third was intermediate. V tended to be related to bilateral and M neurons to contralateral arm movements. The findings seem to support the above view on the role of PMv in visually guided arm movements.

猴子的腹侧运动前皮质(PMV)被认为对手臂的运动施加双侧控制。然而，最近有人提出，PMV是将空间视觉输入转换为运动命令的地方。那么，与双侧手臂运动的表观关系可以被认为是一个更接近于来自两个视觉半球的输入的神经过程。另一方面，如果神经处理更接近于最终的运动命令，神经元的活动预计会与对侧手臂的运动更密切地相关。为了检验这些可能性，在将视觉与运动空间分离的移位棱镜存在的情况下，两只猴子被训练用右臂或左臂到达视觉上呈现的目标。在目标陈述之前，听觉提示指示应该使用哪只手臂来完成任务。在PMV中记录到三种类型的运动相关活动：第一种反映视觉而不是运动的空间(V神经元)；第二种反映运动而不是视觉的空间(M神经元)；第三种是中间的。V神经元与双侧臂运动有关，M神经元与对侧臂运动有关。这些发现似乎支持了上述关于PMV在视觉引导手臂运动中的作用的观点。

项目成果

蔵田 潔: "パーキンソニズムの神経機構" J. Clinical Rehabilitation. 6. 123-126 (1996)

Kiyoshi Kurata：“帕金森症的神经机制”J.临床康复。6. 123-126 (1996)

蔵田 潔: "運動の企画と発現" 臨床科学. 32. 1611-1615 (1996)

Kiyoshi Kurata：“运动的规划和表达”《临床科学》32。1611-1615（1996）。

Kurata, K.: "Set-related activity in the dorsal premotor cortex" Advances in Neurological Sciences. 42. 59-67 (1998)

Kurata, K.：“背侧运动前皮层的设定相关活动”神经科学进展。