The development of degradation methods of signal compounds in bacterial cell-cell communication mechanism for the inhibition of the biofilm formation

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The inhibitory methods of bacterial cell-cell communication mechanism regulates a biofilm formation have been developed for the inhibition of the biofilm formation which causes a lot of environmental and medical problems. Various natural enzymes degrade signal compounds in bacterial cell-cell communication mechanism has been obtained and their usefulness for the inhibition of the biofilm formation has been confirmed. Moreover, the new chemical methods for the trap and/or degrade signal compounds in bacterial cell-cell communication mechanism have been also developed and their usefulness for the inhibition of the biofilm formation has been also confirmed.