The development of degradation methods of signal compounds in bacterial cell-cell communication mechanism for the inhibition of the biofilm formation

为了抑制生物被膜的形成，已经发展了抑制细菌细胞间通讯机制的方法，从而抑制了生物被膜的形成，从而造成了许多环境和医学问题。细菌细胞间通讯机制中降解信号化合物的各种天然酶已被获得，它们在抑制生物被膜形成方面的作用已得到证实。此外，还开发了在细菌细胞-细胞通讯机制中捕获和/或降解信号化合物的新的化学方法，并证实了它们在抑制生物被膜形成方面的有效性。

The inhibitory methods of bacterial cell-cell communication mechanism regulates a biofilm formation have been developed for the inhibition of the biofilm formation which causes a lot of environmental and medical problems. Various natural enzymes degrade signal compounds in bacterial cell-cell communication mechanism has been obtained and their usefulness for the inhibition of the biofilm formation has been confirmed. Moreover, the new chemical methods for the trap and/or degrade signal compounds in bacterial cell-cell communication mechanism have been also developed and their usefulness for the inhibition of the biofilm formation has been also confirmed.