Function of antifreeze protein and dynamic crossover of hydration water

抗冻蛋白的作用与水合水的动态交叉

• 批准号: 22550024
• 负责人: YOSHIDA Koji
• 金额: $ 3万
• 依托单位: Fukuoka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22550024/
• 关键词: 生物物理; 中性子散乱; タンパク質; 水和; 低密度水; 高密度水

The correlation between the antifreeze effect of AFP and the structure and dynamics of hydration water of the protein was studied by X-ray and neutron scatterings (quasi-elastic neutron scattering, inelastic X-ray scattering, and X-ray diffraction) and MD simulation. Although the dynamic transition of the hydrated protein was observed, water structure of hydration water changed insignificantly. Compared with the result of hydration water of the other proteins and confined water in mesoporous materials, the transition between high density water and low density water was discussed.

通过X射线和中子散射（准弹性中子散射、非弹性X射线散射和X射线衍射）以及分子动力学模拟研究了AFP的抗冻作用与蛋白质水化水结构和动力学之间的相关性。虽然观察到水合蛋白质的动态转变，但水合水的水结构变化不显著。通过与其它蛋白质的水化水和介孔材料中的承压水的对比，讨论了介孔材料中高密度水和低密度水的转变。

项目成果

A study of alcohol-induced gelation of beta-lactoglobulin with small-angle neutron scattering, neutron spin echo, and dynamic light scattering measurements.

利用小角中子散射、中子自旋回波和动态光散射测量研究酒精诱导的 β-乳球蛋白凝胶化。

• 发表时间: 2010
• 期刊: Physical Chemistry, Chemical Physics - PCCP
• 作者: K. Yoshida;T. Yamaguchi;N. Osaka;H. Endo;M. Shibayama
• 通讯作者: M. Shibayama

Dynamics of Nano-confined Water

纳米约束水动力学

• 发表时间: 2011
• 作者: K. Yoshida;T. Yamaguchi;S. Kittaka;M.-C. Bellissent-Funel;P. Fouquet
• 通讯作者: P. Fouquet

X-ray diffraction study on monolayer and capillary-condensed acetonitrile in mesoporous MCM-41 at low temperatures

低温介孔MCM-41中单层和毛细管凝聚乙腈的X射线衍射研究

• 发表时间: 2011
• 期刊: J. Mol. Liq
• 作者: T. Yamaguchi;H. Sugino;K. Ito;K. Yoshida;S. Kittaka
• 通讯作者: S. Kittaka

水和タンパク質のX線非弾性散乱

水合蛋白质的 X 射线非弹性散射

• 发表时间: 2012
• 作者: Jun-ichi ADACHI;他;吉田亨次,山口敏男
• 通讯作者: 吉田亨次,山口敏男

Thermal Behavior and Structure of Low-temperature Water Confined in Sephadex G15 Gel by Differential Scanning Calorimetry and X-ray Diffraction Method

• DOI: 10.2116/analsci.29.353
• 发表时间: 2013-03-01
• 期刊: ANALYTICAL SCIENCES
• 影响因子: 1.6
• 作者: Ito, Kanae;Yoshida, Koji;Yamaguchi, Toshio
• 通讯作者: Yamaguchi, Toshio