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Development of pioneering therapy for early atherosclerosis using novel S1P donor

Development of pioneering therapy for early atherosclerosis using novel S1P donor
使用新型 S1P 供体开发早期动脉粥样硬化的开创性疗法
批准号:
22590139
负责人:
FUJII Satoshi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
A novel strategy for conquering atherosclerosis is desirable. Athero-protective HDL is rich in bioactive lipid, sphingosine-1-phosphate (S1P). The effect of S1P on vascular endothelial cells was clarified. The relationship between plasma S1P and vascular endothelial function was evaluated. A newly synthesized biomimetic HDL nanoparticle rich in both S1P and apoA1 exhibited promising anti-inflammatory effects on endothelial cells in culture and on mice challenged with LPS.
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S1Pが血液線溶系に与える影響の解明
阐明S1P对血液纤溶系统的影响
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [真川明将, 岩城壮一郎, 浅井萌子, 榊原大輔, 山村周平, 藤井聡]
通讯作者: 藤井聡
金ナノ粒子を核とした人工 HDL ナノ粒子の調製と物性評価
以金纳米粒子为核心的人工HDL纳米粒子的制备及物性评价
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [高橋 朋弘, 田上 辰秋, 岩城 壮一郎, 藤井 聡, 尾関 哲也]
通讯作者: 尾関 哲也
DOI: --
发表时间: 2012
期刊: Biochimica et Biophysica Acta
影响因子: --
作者: [Sun X, Zhang M, Sanagawa A, Mori C, Ito S, Iwaki S, Satoh H, Fujii S., Sugiura T, Tanaka K, Iwaki S]
通讯作者: Iwaki S
Physicochemical properties of macrogol ointment and emulsion ointment blend developed for regulation of water absorption
为调节吸水率而开发的聚乙二醇软膏和乳液软膏混合物的理化性质
DOI: 10.1016/j.ijpharm.2011.07.034
发表时间: 2011
期刊: Int J Pharmaceut
影响因子: 5.8
作者: [Noda Y, Watanabe K, Sanagawa A, Sobajima Y, Fujii S.]
通讯作者: Fujii S.
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    Research on technological development of narrative communication in public and its applicability
    • 批准号:
      15K14047
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2015
    • 负责人:
      FUJII Satoshi
    • 依托单位:
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    • 批准号:
      26350552
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.16万
    • 财政年份:
      2014
    • 负责人:
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    • 批准号:
      24500434
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2012
    • 负责人:
      FUJII Satoshi
    • 依托单位:
    海外基金