The effects of endogenous adenosine on hippocampal synaptic plasticity induced by low-frequency stimulayion

内源性腺苷对低频刺激诱导的海马突触可塑性的影响

• 批准号: 24500434
• 负责人: FUJII Satoshi
• 金额: $ 2.83万
• 依托单位: Yamagata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24500434/
• 关键词: adenosine; synaptic plasticity; LTP; LTD; hippocampus; NMDA receptors; adenosine A1 receptors; frequency; depotentiation; NMDA receptor; adenosine A1 receptor; astroglia; interneuron; CA1; シナプス可塑性; アデノシン受容体; 海馬

项目成果

Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic receptors in the hippocampus.

细胞外 ATP 调节海马代谢受体激活诱导的突触可塑性。

• 发表时间: 2015
• 期刊: Biomedical Research
• 作者: Yamazaki;Y.; Fujii;S.
• 通讯作者: S.

Increased adenosine levels in mice expressing mutant glial fibrillary acidic protein in astrocytes result in failure of induction of LTP reversal (depotentiation) in hippocampal CA1 neurons.

在星形胶质细胞中表达突变型胶质纤维酸性蛋白的小鼠中，腺苷水平升高导致海马 CA1 神经元 LTP 逆转（去电位）诱导失败。

• DOI: 10.1016/j.brainres.2014.07.005
• 发表时间: 2014
• 期刊: Brain Res
• 影响因子: 2.9
• 作者: Fujii S;Tanaka KF;Ikenaka K;Yamazaki Y.
• 通讯作者: Yamazaki Y.

Metabotropic glutamate receptors

• DOI: 10.1007/s00726-006-0315-0
• 发表时间: 2007-01
• 期刊: Amino Acids
• 影响因子: 3.5
• 作者: Andrzej Pilc;K. Ossowska

Modulation of synaptic plasticity by the coactivation of spatially distinct synaptic inputs in rat hippocampal CA1 apical dendrites

大鼠海马 CA1 顶端树突空间不同突触输入的共激活对突触可塑性的调节

• DOI: 10.1016/j.brainres.2013.05.023
• 发表时间: 2013
• 期刊: Brain Research
• 影响因子: 2.9
• 作者: Masashi Kondo;Tatsuo Kitajima;Satoshi Fujii;Minoru Tsukada;Takeshi Aihara
• 通讯作者: Takeshi Aihara

NMDA receptor-mediated Ca(2+) influx triggers nucleocytoplasmic translocation of diacylglycerol kinase ζ under oxygen-glucose deprivation conditions, an in vitro model of ischemia, in rat hippocampal slices

NMDA 受体介导的 Ca(2+) 内流在缺氧-葡萄糖条件下（体外缺血模型）大鼠海马切片中触发二酰甘油激酶 z 的核质转位

• DOI: 10.1007/s00418-011-0907-y
• 发表时间: 2012
• 期刊: Histochem CellBiol
• 作者: Suzuki Y;Yamazaki Y;Hozumi Y;Okada M;Tanaka T;Iseki K;Ohta N;Aoyagi M;Fujii S;Goto K.
• 通讯作者: Goto K.