课题基金 / 基金详情

Establishment of a novel therapeutic strategyfor atherosclerosis via soluble lipid transporter.

Establishment of a novel therapeutic strategyfor atherosclerosis via soluble lipid transporter.
通过可溶性脂质转运蛋白建立动脉粥样硬化的新治疗策略。
批准号:
22590832
负责人:
UEHARA Yoshinari
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

UEHARA Yoshinari的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Our previous report shows the microglial ATP-binding cassette transporter(ABC) G4 has been upregulated in Alzheimer's disease (AD) brain. We had reported the cloning of a novel isoform of human ABCG4 which was short-isoform (SI) of ABCG4. SI-ABCG4 transfected cells expressed SI-ABCG4 proteins with both soluble and membrane bound forms. The SI-ABCG4 is possible to suppress HDL-mediated cholesterol efflux to interact with other lipid transporters such as ABCG1, ABCG4, and ABCA1. SI-ABCG4 could be a therapeutic tool and a novel marker foratherosclerosis related diseases.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
FAMP, A Promising Anti-atherosclerotic Agent Construct Pre-Beta HDL in vitro and in vivo
FAMP,一种有前途的抗动脉粥样硬化剂,体外和体内构建 Pre-Beta HDL
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Y. Uehara, K. Oniki, H. Tanigawa, S. Abe, S. Ando, E. Yahiro, SI. Miura, K. Saku]
通讯作者: K. Saku
IDENTIFICATION AND CLONING OF NOVEL SOLUBLE AND MEMBRANE BOUND FORMS OF HUMAN ATP-BINDING CASSETTE TRANSPORTER G4
新型可溶性和膜结合形式的人 ATP 结合盒转运蛋白 G4 的鉴定和克隆
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Y.Uehara, S.Abe, E.Yahiro, A.Kawamura, T.Iwamoto, SI.Miura, K.Saku]
通讯作者: K.Saku
Novel Molecular Imaging of Atherosclerosis with 68Ga-Labeled Apo A-I Mimetic Peptide and PET
使用 68Ga 标记的 Apo A-I 模拟肽和 PET 进行动脉粥样硬化的新型分子成像
DOI: --
发表时间: 2013
期刊: Circ J
影响因子: 3.3
作者: [Mitsuo Kinugasa, Yoshiyuki Rikitake, Yusuke Kurogane, Fumie Kureha, Seimi Kobayashi, Ken-ichi Hirata, Kawachi E; Uehara Y; Hasegawa K; Yahiro E; Ando S; Wada Y; Yano T; Nishikawa H; Shiomi M; Miura S; Watanabe Y; Saku K]
通讯作者: Kawachi E; Uehara Y; Hasegawa K; Yahiro E; Ando S; Wada Y; Yano T; Nishikawa H; Shiomi M; Miura S; Watanabe Y; Saku K
DOI: 10.1161/jaha.113.000048
发表时间: 2013-05-24
期刊: Journal of the American Heart Association
影响因子: 5.4
作者: [Uehara Y, Ando S, Yahiro E, Oniki K, Ayaori M, Abe S, Kawachi E, Zhang B, Shioi S, Tanigawa H, Imaizumi S, Miura S, Saku K]
通讯作者: Saku K
9
    Beneficial effects of aerobic exercise on HDL metabolism and cellular mitochondria function by an improvement of HDL function.
    • 批准号:
      17K01772
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2017
    • 负责人:
      UEHARA Yoshinari
    • 依托单位:
    A novel function of membrane cholesterol transporter and a therapeutic strategy for atherosclerosis
    • 批准号:
      19590874
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2007
    • 负责人:
      UEHARA Yoshinari
    • 依托单位:
    海外基金