The role of neuronal and inducible NOS in the regulation of intestinal apoptosis in fasting and refeeding rat
The role of neuronal and inducible NOS in the regulation of intestinal apoptosis in fasting and refeeding rat
批准号:
22591492
负责人:
UCHIDA Hiroyuki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
To investigate the change and role of inducible nitric oxide synthase (iNOS) and neuronal nitric oxide synthase (nNOS) on decreasing intestinal apoptosis of refeeding after fasting in rats and to define whether the recovery of the intestinal mucosa atrophy by refeeding is associated with the levels of nitric oxide synthases (NOSs) in the jejunum. These results suggest that nNOS-involved control might be present in the regulation of iNOS activity and its-mediated apoptosis in fasting and refeeding.
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Fasting-induced intestinal apoptosis is mediated by inducible nitric oxide synthase and interferon-r in rat
诱导型一氧化氮合酶和干扰素-r 介导大鼠禁食诱导的肠细胞凋亡
DOI:
--
发表时间:
2010
期刊:
Am J Physiol Gastrointest liver Physiol
影响因子:
--
作者:
[J Ito, H Uchida, et.al]
通讯作者:
et.al
The role of neuronal and inducible NOS in the regulation of intestinal apoptosis in fasting and refeeding rat.
神经元和诱导型 NOS 在调节禁食和再喂养大鼠肠道细胞凋亡中的作用。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Junta Ito, Hiroyuki Uchida, et.al.]
通讯作者:
et.al.
酸化ストレスを介した絶食時の廃用性腸管粘膜萎縮に対するグルタミンの予防効果
谷氨酰胺对氧化应激介导的禁食期间废用性肠粘膜萎缩的预防作用
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[町田保奈美, 内田博之ら]
通讯作者:
内田博之ら
絶食後再摂食ラットにおける血漿コルチコステロンレベルと糖代謝に対する一酸化窒素の関与
一氧化氮对禁食后重新喂养的大鼠血浆皮质酮水平和葡萄糖代谢的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[町田保奈美, 内田博之ら, 内田博之]
通讯作者:
内田博之
再摂食による腸管粘膜の回復過程における誘導型NO合成酵素(iNOS)によるアポトーシスの制御
再喂养引起的肠粘膜恢复过程中诱导型一氧化氮合酶(iNOS)对细胞凋亡的控制
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[伊東順太、内田博之, ら]
通讯作者:
ら
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