Evaluation of frontal lobe function in patients with panic disorder with agoraphobia using near infrared spectroscopy

对伴广场恐怖症的惊恐障碍患者进行每2周4次的认知行为治疗，用近红外光谱仪测量每次治疗前后观看焦虑刺激和中性刺激视频时脑血流量的变化。暴露一段时间后，颞区的氧合血红蛋白减少。证实治疗过程中脑功能的变化可以通过近红外光谱分析进行测量，认为与症状改善有关。

The cognitive behavior therapy of four sessions every two week was performed in the patients with panic disorder with agoraphobia, and the change of cerebral blood volume at the time of watching the video of an anxious stimulus and a neutral stimulus before and after each session were measured using near infrared spectroscopy. The oxy-hemoglobin of the temporal region decreased after the session of an exposure. It was confirmed that the change of brain function of a treatment process can be measured by near infrared spectroscopy, and it was thought that it related to the symptom improvement.