VASOHIBIN1 expression and function in the nasal tissue

Vasohibin-1是一种负调控血管生成的新型功能分子。我们的初步实验提示Vasohibin-1可能参与嗅觉受体的表达，因此我们验证了Vasohibin-1在鼻组织中的表达。虽然我们通过RT-PCR和免疫染色法证实了Vasohibin-1在小鼠鼻组织中有表达，但在嗅细胞中没有表达，只在内皮细胞中表达。没有得到支持我们关于Vasohibin-1调控嗅觉受体的假设的结果。

Vasohibin-1 has been reported as a novel functional molecules which negatively regulated angiogenesis. It was suggested by our preliminary experiment that Vasohibin-1 might be involved in the expression of the olfactory receptor, so we verified the expression of Vasohibin-1 in the nasal tissue. Although we confirmed Vasohibin-1 expression in mouse nasal tissue by RT-PCR and immunostaining method, it was not observed on olfactory cells but endothelial cells. The result which supported our hypothesis of the regulation the olfactory receptor by Vasohibin-1 was not obtained.