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Osteocytic regulation on osteoclastic bone resorption and survival/death of osteocytes

Osteocytic regulation on osteoclastic bone resorption and survival/death of osteocytes
骨细胞对破骨细胞骨吸收和骨细胞存活/死亡的调节
批准号:
22791760
负责人:
SUZUKI Reiko
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
Osteocytes are shown to synthesize sclerostin and dentin matrix protein-1 (DMP-1), which serve to inhibit osteoblastic activities and subsequent bone remodeling, and regulate surrounding mineralization by binding to calcium ion of calcium phosphate crystals in bone, respectively. In a state of accelerated bone resorption, osteocytes decreased sclerostin synthesis in accordance with stimulated osteoclastic activities. The decreased synthesis of sclerostin appears to be not interrupt accelerated osteoclastic bone resorption by mediating osteoblasts.
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细胞牙骨质层状结构的扫描和透射电子显微镜研究。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [山本恒之, 李敏啓, 郭頴, 柳鋳晟, 増木英郎, 長谷川智香, 鈴木礼子, 網塚憲生]
通讯作者: 網塚憲生
Histological review of the human cellular cementum with special reference to an alternating lamellar pattern
人类细胞牙骨质的组织学审查,特别参考交替层状模式
DOI: 10.1007/s10266-010-0134-3
发表时间: 2010
期刊: Odontol
影响因子: --
作者: [Yamamoto T., Li M., Liu Z., Guo Y., Hasegawa T., Masuki H., Suzuki R., Amizuka N]
通讯作者: Amizuka N
DOI: 10.2220/biomedres.31.307
发表时间: 2010-10-01
期刊: BIOMEDICAL RESEARCH-TOKYO
影响因子: 1.2
作者: [Masuki, Hideo, Li, Minqi, Amizuka, Norio]
通讯作者: Amizuka, Norio
Morphological aspects of the biological function of the osteocytic lacunar canalicular system and of osteocyte-derived factors.
骨细胞腔隙小管系统和骨细胞衍生因子的生物学功能的形态学方面。
DOI: --
发表时间: 2012
期刊: Oral Science International.
影响因子: --
作者: [Sasaki M., Hongo H., Hasegawa T., Suzuki R., Liu Z., Freitas PHL., Yamada T., Oda K., Yamamoto T., Li M., Totsuka Y., Amizuka N.]
通讯作者: Amizuka N.
20
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