Establishment and analysis of cancer stem cell and induced cancer stem cell of refractory pediatric solid organ neoplasm.
Establishment and analysis of cancer stem cell and induced cancer stem cell of refractory pediatric solid organ neoplasm.
批准号:
22791713
负责人:
YAMAMOTO Yuki
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
流式细胞仪和实时荧光定量PCR检测发现横纹肌肉瘤细胞系RD和Rh30有大量的EGFR阳性细胞,而Kym-1和RMS-ym有少量的EGFR阳性细胞,西妥昔单抗和放线菌素D联合应用抑制细胞生长与EGFR阳性细胞株有很强的协同作用。两种试剂联合使用可增加EGFR阳性细胞的凋亡率。
英文摘要
We found that Rhabdomyosarcoma cell line, RD and Rh30 have a large number of EGFR positive cells, whereas KYM-1 and RMS-YM have small number of EGFR positive cells by FACS and real time PCR.The combination of cetuximab and actinomycin D was highly synergistic in inhibiting cell growth with EGFR positive cell line. The combination of two reagents increased rates of apoptosis to EGFR positive cells.
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会议论文
Economic analysis of forest fire in Indonesia: Policy evaluation with randomized field experiment.
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批准号:16K17127
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.41万
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财政年份:2016
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负责人:YAMAMOTO Yuki
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依托单位:
Study in Tissues Damage by Phenol and TCA Peels and clinical applications
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批准号:15591188
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:2003
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负责人:YAMAMOTO Yuki
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依托单位:
海外基金