Can epigenetics be the material of adaptive evolution? -Focusing wild Arabidopsis-

集中分布在海拔30 ~ 3000 m的拟南芥；我们(1)在田间移植实验中阐明了适应性进化已经发生；(2)在室内生长实验中阐明了开花和发芽时间的海拔梯度；(3)在室内生长实验中量化了开花时间的表型可塑性；(4)揭示了母本个体开花时间随环境的变化。(5)鉴定出3个等位基因频率随海拔高度发生显著差异的“海拔适应基因”；(6)取样DNA，利用亚硫酸处理和下一代测序启动表观遗传分析系统，研究不同环境下的表观遗传变异。

Focusing Arabidopsis kamchatica that is distributed over 30 - 3000 m altitude; we (1) clarified adaptive evolution had already occurred in the field transplant experiment, (2) clarified altitudinal cline in flowering and germination timing in the laboratory growth experiment, (3) quantified phenotypic plasticity in flowering timing in the laboratory growth experiment, (4) indicated the change in flowering timing depending on environment that maternal individuals experienced, (5) identified three "altitude adaptation genes" whose allele frequencies were drastically differentiated along altitude, and (6) sampled DNA and initiated epigenetics analytical system utilizing bisulphate treatment and next-generation sequencing, for investigating epigenetic variation across different environmente.