The role of long chain fatty acid : amino acid conjugation in insulin resistance
The role of long chain fatty acid : amino acid conjugation in insulin resistance
批准号:
22790097
负责人:
ITO Takashi
金额:
$2.58万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
We evaluated the impacts of taurine deficiency to high fat diet-induced pathology by using taurine transporter knockout mice. The present studies indicate that taurine deficiency improve high fat diet-induced glucose intolerance and insulin resistance. Moreover, our data suggest that taurine deficiency causes inefficient energy production in tissues, which results in the improvement against high fat diet-induced pathology.
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タウリントランスポーターノックアウトマウスにおけるトレッドミル運動中の基質代謝応答の変化
牛磺酸转运蛋白敲除小鼠跑步机运动过程中底物代谢反应的变化
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Chiang Ju Jong, et al., 木根啓多, 花畑友規, 宮崎奈津子, 山谷安奈, 吉川夏未, 木根啓多, 花畑友規, 宮崎奈津子, 山谷安奈, 吉川夏未, 伊藤崇志]
通讯作者:
伊藤崇志
タウリン欠乏マウス心筋における遺伝子発現変動の解析
牛磺酸缺陷小鼠心肌基因表达变化分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Chiang Ju Jong, et al., 木根啓多]
通讯作者:
木根啓多
タウリン欠乏マウスにおける加齢依存的な心繊維化の亢進
牛磺酸缺陷小鼠心脏纤维化的年龄依赖性增强
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Chiang Ju Jong, et al., 木根啓多, 花畑友規]
通讯作者:
花畑友規
タウリン欠乏の創傷治癒への影響
牛磺酸缺乏对伤口愈合的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Chiang Ju Jong, et al., 木根啓多, 花畑友規, 宮崎奈津子, 山谷安奈, 吉川夏未, 木根啓多, 花畑友規, 宮崎奈津子, 山谷安奈, 吉川夏未, 伊藤崇志, 伊藤崇志, 宮崎奈津子]
通讯作者:
宮崎奈津子
Taurine depletion-related cardiomyopathy in animals
动物牛磺酸耗竭相关心肌病
DOI:
--
发表时间:
2011
期刊:
Cardiomyopathy-From Basic Research to Clinical Management
影响因子:
--
作者:
[Takashi Ito, Stephen W. Schaffer, Junichi Azuma, Takashi Ito, Takashi Ito]
通讯作者:
Takashi Ito
共 18 条
A novel therapeutic strategy targeting HMGB1 isoforms in sepsis
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批准号:18H02904
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项目类别:Grant-in-Aid for Scientific Research (B)
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负责人:ITO Takashi
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A Comprehensive Analysis of Direct Democracy in the Case of Local Government and Referendums in Osaka through Repeated Cross-sectional Surveys
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Chromatin remodeling and Induction of pluripotency via Sox2/TBP complex
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Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells
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资助金额:$2.5万
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负责人:ITO Takashi
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A history of animal welfare in modern Britain
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批准号:16K03108
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资助金额:$3.0万
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Therapeutic strategy targeting extracellular histones in sepsis-associated DIC
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Extracellular histones stimulate endothelial cells to release unusually-large von Willebrand factor multimer: mechanistic insight into the pathogenesis of lethal coagulopathy
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Extracellular histones as a myocardial depressant factor
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Transomic analysis of adaptation induced by a synthetic gene circuit
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HMGB1-induced vaspressin deficiency contributes to septic shock
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A role of extracellular histones as mediators of death in sepsis
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Improvement of the flypast method for pulsed muSR measurements on a small amount of sample
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Fecal microflora composition change in neonates with intensive theraphy
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Role of CDC42 in pro-inflammatory phenotype of senescent vascular endothelial cells
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Genome-wide in vivo footprinting by next-generation sequencing
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Development of Oral Infection Control System with Natural and Artificial materials
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A Study on the Making of Inventory of the Various Disaster Revival Projects and their Transformation Processes Based on the Chronological Order
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Genome-wide analysis of chromatin structure at single molecule resolution by base modification and next-generation sequencing
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Politics of animal ethics in modern Britain
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