The development of the new bone regeneration therapy for the diabetic osteoporosis

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Using diabetes mellitus / an osteoporosis complication model animal, we analyzed the factor which was necessary for a bone regeneration in the bone regeneration part limited part and performed this study for the purpose of developing bone regeneration medical treatment with the drug delivery system. An ostosis by Cal Sane and the alizarin was confirmed even if we employed it in the aperture of either carrier. And the bony formation in the honeycomb aperture was seen a lot in Col37H in comparison with 37H.Col37H compared the bone density with 37H in 1 week later, and density was slightly high. Elevation of the manifestation of BMP-2 in the periodontal disease alveolar part of mandible alveolar bone and VEGF was observed.