Synthesis of highly functionalized compounds through electron transfer processes free from heavy metals and rare metals

在镁的促进下，芳香族羰基化合物与三氟乙酸乙酯的还原偶联反应导致含氟有机化合物的选择性生成。一般来说，含氟化合物的合成并不容易，但在这些反应中可以通过使用更便宜的含氟试剂来实现。芳香族羰基化合物与二氧化碳的还原偶联反应通过碳-碳键的形成得到了羧化化合物。镁促进的还原三氟乙酰化反应高产率地合成了6-三氟乙酰天青烯。

Mg-promoted reductive coupling of aromatic carbonyl compounds and ethyl trifluoroacetate brought about selective formation of fluorine-containing organic compounds. In general, the synthesis of fluorinated compounds is not easy, but it could be achieved by use of cheaper fluorine-containing reagents in these reactions. The reductive coupling reaction of aromatic carbonyl compounds and carbon dioxide gave the carboxylated compounds through the carbon-carbon bond formation. Mg-promoted reductive trifluoroacetylation of azulene led to the synthesis of 6-trifluoroacetylazulene in good yield.