Basic study to understand "molecular mimicry" of the host by parasitic wasp embryos

一种多胚胡蜂Copidosoma floridanum胚胎相容地侵入宿主胚胎。这表明宿主胚胎细胞通过细胞表面的分子识别入侵的黄蜂胚胎。在这里，我们建立了一个体外黄蜂进入抑制试验，发现E-钙粘蛋白和C-型凝集素的黄蜂胚胎参与其入侵到宿主胚胎。对C.还分析了floridanum E-钙粘蛋白和与细胞外基质相关的相关分子。

A polyembryonic wasp Copidosoma floridanum embryo compatitibly invades the host embryo. This suggests that the host embryonic cells recognize the invading wasp embryo by molecules on the cell surface. Here we developed an in vitro wasp entry inhibition assay and found that E-cadherin and C-type lectins of the wasp embryo were involved in their invasion into the host embryo. The molecular characterization of C. floridanum E-cadherin and related molecules associated with the extracellular matrix were also analysed.