Brain temperature measured by proton magnetic resonance spectroscopy evaluates as a parameter of cerebral hemodynamic impairment in patients with chronic major cerebral artery steno-occlusive disease : Comparison with positron emission tomography

质子磁共振波谱测量的脑温度作为慢性大脑大动脉狭窄闭塞性疾病患者脑血流动力学损伤的参数进行评估：与正电子发射断层扫描的比较

• 批准号: 22700436
• 负责人: NISHIMOTO Hideaki
• 金额: $ 1.91万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22700436/
• 关键词: 脳温; 脳循環代謝; MRS; 脳温map; PET

The aim of this study is to estimate cerebral hemodynamic impairment by measurement of brain temperature(BT) using proton magnetic resonance spectroscopy compared with positron emission tomography in patient with chronic major cerebral artery steno-occlusive disease. There was significant correlation between▲BT(▲BT in the affected cerebral hemisphere. BT in the contralateral cerebral hemisphere) and cerebral blood volume(CBV) ratio(ratio of CBV in the affected cerebral hemisphere to that in the contralateral cerebral hemisphere). There was a significant correlation between▲BT and oxygen extraction fraction ratio.

本研究的目的是评估脑血流动力学损害的测量脑温度（BT）使用质子磁共振波谱与正电子发射断层扫描相比，在慢性主要脑动脉狭窄闭塞性疾病的患者。患侧大脑半球的▲BT（▲BT）之间存在显著相关性。对侧大脑半球的BT）和脑血容量（CBV）比（受累大脑半球的CBV与对侧大脑半球的CBV之比）。▲BT与氧提取分数比呈显著正相关。

项目成果

Brain Temperature Measured by Using Proton MR Spectroscopy Predicts Cerebral Hyperperfusion after Carotid Endarterectomy

• DOI: 10.1148/radiol.10090930
• 发表时间: 2010-09-01
• 期刊: RADIOLOGY
• 影响因子: 19.7
• 作者: Murakami, Toshiyuki;Ogasawara, Kuniaki;Ogawa, Akira
• 通讯作者: Ogawa, Akira

虚血性脳血管障害に対するMRSによる脳温度測定の臨床応用

磁共振脑部温度测量在缺血性脑血管病中的临床应用

• 发表时间: 2010
• 作者: 西本英明;吉岡芳親;石垣大哉;藤原俊朗;吉田研二;小林正和;小笠原邦昭
• 通讯作者: 小笠原邦昭