Development of genetic analysis method for risk diagnosis for multifactorial disease and drug response
Development of genetic analysis method for risk diagnosis for multifactorial disease and drug response
批准号:
22710191
负责人:
NISHIDA Nao
金额:
$2.25万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
High-throughput and highly accurate SNP typing platforms are required to perform risk diagnosis for multifactorial disease and drug response. Here, we improve the DigiTag2 assay to shorten the running time and save the running cost by applying new type of enzyme. The DigiTag2 assay enables analysis of a set of 96 SNPs using Kapa 2GFast HotStart DNA polymerase with a new protocol that has a total running time of about 7 hours, which is 6 hours shorter than the previous protocol.
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DOI:
10.1371/journal.pone.0020589
发表时间:
2011
期刊:
PloS one
影响因子:
3.7
作者:
[Kurotaki N, Tasaki S, Mishima H, Ono S, Imamura A, Kikuchi T, Nishida N, Tokunaga K, Yoshiura K, Ozawa H]
通讯作者:
Ozawa H
C型慢性肝炎に対するペグインターフェロン+リバビリン併用療法の有効性を規定するホスト側遺伝要因の同定
确定决定聚乙二醇干扰素+利巴韦林联合治疗慢性丙型肝炎有效性的宿主遗传因素
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Morito D., Nishikawa K., (10名省略), Nagata K., 西田奈央,田中靖人,杉山真也,小池麻子,提嶋恵美,小笠原有子,石橋良美,柴田靖加,溝上雅史,徳永勝士]
通讯作者:
西田奈央,田中靖人,杉山真也,小池麻子,提嶋恵美,小笠原有子,石橋良美,柴田靖加,溝上雅史,徳永勝士
A genome-wide association study identifies the ass ociation of HLA-DP locus with chro nic hepatitis B and viral clearance
全基因组关联研究确定了 HLA-DP 位点与慢性乙型肝炎和病毒清除的关联
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Nishida N, Sawai H, Mawatari Y, Y amaoka M, Koike A, Matsuura K, T anaka Y, Sugiyama M, Ito K, Mizok ami M, Tokunaga K]
通讯作者:
Tokunaga K
A genome-wide association study identifies the association of HLA-DP locus with chronic hepatitis B and viral clearance
全基因组关联研究确定了 HLA-DP 位点与慢性乙型肝炎和病毒清除的关联
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Nao Nishida, Hiromi Sawai, Yoriko Mawatari, Megumi Yamaoka, Asako Koike, Kentaro Matsuura, Yasuhito Tanaka, Masaya Sugiyama, Kiyoaki Ito, Masashi Mizokami, Katsushi Tokunaga]
通讯作者:
Katsushi Tokunaga
DOI:
10.1186/1471-2156-12-29
发表时间:
2011-03-07
期刊:
BMC GENETICS
影响因子:
2.9
作者:
[Koike, Asako, Nishida, Nao, Tokunaga, Katsushi]
通讯作者:
Tokunaga, Katsushi
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