Development of minimally invasive ablation treatment system of tongue cancer using an AC magnetic field

交流磁场舌癌微创消融治疗系统的研制

• 批准号: 23500559
• 负责人: NAOHARA TAKASHI
• 金额: $ 3.41万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23500559/
• 关键词: 癌治療; 焼灼療法; 交流磁場誘導法; チタン被覆磁性体針; 生体等価ファントム; 磁界解析シミュレーション; 熱伝達シミュレーション; 焼灼用磁性体針; ハイパーサーミア; 発熱シミュレーション; 動物実験

To develop a novel ablation treatment system of tongue cancer, the heating properties of a prototype Ti-coated needle with a 26.5mm length were investigated in an AC magnetic field. The effect of the inclination angle was completely eliminated in the newly designed needle, suggesting that the non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature. In the magnetic field analysis, simulation images of the current density and Joule loss density were obtained for the prototype Ti-coated ablation needle. Moreover, the heat transfer behavior was simulated for the tissue-mimicking phantom subjected to the insertion of the prototype Ti-coated ablation needle in order to visualize their temperature distribution.

为了开发一种新的舌癌消融治疗系统，对26.5 mm长的镀钛针头在交流磁场中的加热特性进行了研究。在新设计的针中完全消除了倾角的影响，表明相对于磁通方向的无定向加热特性允许精确控制烧蚀温度。在磁场分析中，得到了原型镀钛烧蚀针的电流密度和焦耳损耗密度的仿真图像。此外，还模拟了模拟组织体模在原型钛涂层烧蚀针插入后的传热行为，以直观地显示其温度分布。

项目成果

Heat Transfer Behavior of Ti-coated Carbon Steel Rod for Ablation Therapy of Tongue Cancer Utilizing High-frequency Induction Technique

高频感应技术用于舌癌消融治疗的镀钛碳钢棒的传热行为

• 发表时间: 2013
• 期刊: Proceedings of The International Conference on Heating by Electromagnetic Sources
• 作者: T. Naohara;H. Aono;T. Maehara;H. Hirazawa;S. Matsutomo;Y. Watanabe
• 通讯作者: Y. Watanabe

癌の高周波誘導焼灼療法に用いるチタン被覆磁性体針の発熱特性

钛涂层磁针在癌症射频感应消融治疗中的发热特性

• 发表时间: 2011
• 作者: 猶原隆;青野宏通;前原常弘;渡部祐司;平澤英之;松友真哉
• 通讯作者: 松友真哉

Development of ti-coated ferromagnetic needle, adaptable for ablation cancer therapy by high-frequency induction heating.

• DOI: 10.3390/jfb3010163
• 发表时间: 2012-03-06
• 期刊: Journal of functional biomaterials
• 影响因子: 4.8
• 作者: Naohara T;Aono H;Maehara T;Hirazawa H;Matsutomo S;Watanabe Y
• 通讯作者: Watanabe Y

High-frequency induction heating of Ti-coated mild steel rod for miniimally invasive ablation therapy of human cancer

高频感应加热镀钛低碳钢棒用于人类癌症微创消融治疗

• 发表时间: 2013
• 期刊: Journal of Magnetism and Magnetic Materials
• 影响因子: 2.7
• 作者: N.Endoh;T.Tsuchiya;S.Tanaka;and S.Sakuma;T. Naohara 他6名
• 通讯作者: T. Naohara 他6名

High-Frequency Induction Heating of Needle-Shaped Mg-Ferrite for Ablation Therapy of Human Cancer

针状镁铁氧体高频感应加热用于人类癌症消融治疗

• 发表时间: 2012
• 期刊: Journal of Iron and Steel Research, International
• 作者: M. Yoshida;M. Sato;Y. Yamamoto;T. Maehara;T. Naohara;H. Aono;H. Sugishita;K. Sato;Y. Watanabe;Ｔ．Ｎａｏｈａｒａ 他5名
• 通讯作者: Ｔ．Ｎａｏｈａｒａ 他5名