Behavior modification program using longevity-associated mitochondrial DNA polymorphism data

长寿相关的线粒体DNA 5178 C/A多态性改变了饮酒对高低密度脂蛋白胆固醇血症的影响、吸烟对血脂异常风险的影响、饮酒或吸烟对血清非高密度脂蛋白胆固醇水平的影响、绿茶对高血压风险的影响、饮酒或绿茶对肾小球滤过率的影响。以及饮酒或喝咖啡对心血管危险因素聚集的影响。希望这些发现将有助于建立个性化的行为矫正计划，以预防与生活方式相关的疾病。

Longevity-associated mitochondrial DNA 5178 C/A polymorphism modifies the effects of alcohol consumption on hyper-LDL cholesterolemia, the effects of cigarette smoking on the risk of dyslipidemia, the effects of alcohol consumption or cigarette smoking on serum non-HDL cholesterol levels, the effects of green tea consumption on the risk of hypertension, the effects of alcohol consumption or green tea consumption on the estimated glomerular filtration rate, and the effects of alcohol consumption or coffee consumption on the clustering of cardiovascular risk factors. It is hoped that these findings will contribute to the establishment of personalized behavior modification programs for the prevention of lifestyle-related diseases.