Exhaustive risk evaluation of trans-fatty acid and glycidol fatty acid esther

在部分食用油中检出反式脂肪酸(TFA)(0.3-1.93g/100g)。然而，加热会降低TFA的浓度。虽然在油中检测到缩水甘油脂肪酸酯(GE)，但加热也会降低GE的水平。在Ames试验(TA100)、彗星试验和微核试验中，与未处理组相比，Ge处理组表现出显著的遗传毒性(突变、DNA损伤和微核率)。炭火加热的粉碎猪肉中锗含量很高(195g/100g肉)。这些结果表明，我们从日常食物中习惯性地接触到了TFA和GE，这两种物质对人体健康有影响。估计这些化学品对人类的风险是很重要的。

Trans-fatty acid (TFA) was detected in some dietary oils (0.3-1.93g/100g). However, the concentration of TFA was decreased by heating. Though glycidol fatty acid ester (GE) was determined in oils, the levelof GE was also decreased by heating. Treatment of GE showed the siginificantly genotoxcities (reverse mutation, DNA damages and the frequency of micronuclei) in Ames test(TA100), COMET assay and micronuclei test compared to non-treated groups. The concentration of GE in comminuted pig meat heated with charcoal firewas very high (195g/100g meat). From these results, it is demonstrated that we are habitually exposed to TFA and GE that have an influence on the health of human from daily foods. It is important to estimate the risk of these chemicals to human.