Clinical efficacy of doronary CT angiography using dual-source CT

双源CT冠状动脉CT血管造影的临床疗效

• 批准号: 23591770
• 负责人: MATSUNAGA Naofumi
• 金额: $ 3.33万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591770/
• 关键词: マルチスライスCT; 冠動脈CT angiography; 急性冠症候群; ２管球ＣＴ; 冠動脈狭窄; 時間分解能; 石灰化プラーク; 高心拍; 冠動脈カテーテル検査; 冠動脈プラークイメージ; 石灰化plaque; 石灰化スコア; 心臓CT; 心拍; 冠動脈石灰化; signal-to-noise比(SNR); contrast-to-noise比(CNR); 被曝低減; ベータ遮断薬; ２管球CT

Relatively good quality of dual-source CT (DSCT) was obtained in patients with more than 100 bpm without use of beta blocker. DSCT showed a significantly better image quality than single-source CT (SSCT), especially in patients with low heart rates. The image quality of DSCT was significantly lower on a per vessels basis for all vessels than SSCT. The image reconstruction at the phase of isovolumetric relaxation time (IRT) is feasible in DSCT, because of its temporal resolution of 83 ms. High temporal resolution of DSCT shows equivalent accuracy of coronary stenosis detection to SSCT without reducing heart rate, because of its image reconstruction at IRT. The coronary artery was vasodilated and evaluable segments was increased in number by administration of the nitroglycerin. The segment with coronary plaque was not fully dilated, allowing the differentiation from the normal segment.

在不使用受体阻滞剂的情况下，超过100 bpm的患者获得了相对较好的双源CT （DSCT）质量。DSCT的图像质量明显优于单源CT (SSCT)，特别是在低心率患者中。在所有血管的基础上，DSCT的图像质量明显低于SSCT。等体积松弛时间（IRT）阶段的图像重建在DSCT中是可行的，因为它的时间分辨率为83 ms。高时间分辨率DSCT在不降低心率的情况下显示出与SSCT相同的冠状动脉狭窄检测精度，因为它在IRT下进行了图像重建。硝酸甘油使冠状动脉血管扩张，可评估节段数目增加。有冠状动脉斑块的节段未完全扩张，使其与正常节段分化。