The correlation between FDG uptake and various oncogenes expression in pancreas cancer

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We examined correlation among FDG uptake indices (SUVmax), MRI diffusion index(ADC) and various oncogenes expression in pancreas cancer. In addition, we evaluated the association those parameters and prognoses.Positive weak correlations were noted among SUVmax and EGFR, Ki-67, CDH13, VEGFA, p53.The value of SUV max was significantly higher in the recurrent group compared with that of the non-recurrence group. As for ADC mean level, it was significantly lower in the recurrent group. Both CDH13 and VEGFA demonstrated significantly higher values in the recurrent group.In pancreas cancer, gene expressions such as involving in tumor-vascular proliferation and tissue adhesion were the important prognostic factor.In addition, both SUV max and ADC mean were important imaging biomarker for predicting prognosis.