Animal implant research on small suturing device which eliminates knot tying

免打结小型缝合器的动物植入研究

• 批准号: 23592029
• 负责人: ONO Minoru
• 金额: $ 3.24万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592029/
• 关键词: 低侵襲手術; 冠状動脈バイパス術; 内視鏡手術; ロボット手術; 血管吻合; 吻合デバイス

We developed a new suturing device which enables to perform coronary artery bypass surgery under endoscopic and/or robotic assistance. First, we confirmed sufficient stretch-resistant forces and acceptable biological safety of this device. Then, we created chronic models of rabbit carotid artery bypass using jugular vein and swine off-pump coronary artery bypass using bilateral internal thoracic arteries, comparing regular suture and this new device. Graft patency and grade of inflammatory cell infiltration were similar between two groups. Thereby, it was shown that this new suturing device is safe and effective. Evaluation of efficacy of this suturing device in endoscopic and/or robotic condition is warranted.

我们开发了一种新的缝合装置，该装置使能够在内窥镜和/或机器人辅助下进行冠状动脉搭桥手术。首先，我们证实了该设备的足够耐药力和可接受的生物学安全。然后，我们使用双侧胸部胸部动脉创建了兔颈动脉旁路的慢性模型，并使用颈部冠状动脉旁路搭桥，比较了常规缝合线和这种新装置。两组之间的移植物通畅性和炎症细胞浸润等级相似。因此，这表明这种新的缝合设备是安全有效的。有必要评估该缝合装置在内窥镜和/或机器人条件下的功效。