Development of new treatment for chondrosarcoma by targeting sarcoma stem cells

通过靶向肉瘤干细胞开发软骨肉瘤新疗法

• 批准号: 23592192
• 负责人: MATSUMOTO Yoshihiro
• 金额: $ 3.41万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-28 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592192/
• 关键词: 軟骨肉腫; 肉腫幹細胞; 骨軟部腫瘍; 薬剤耐性; 癌幹細胞; 悪性骨軟部腫瘍; 腫瘍幹細胞

项目成果

Clinical outcome for patients with dedifferentiated chondrosarcoma: a report of 9 cases at a single institute.

• DOI: 10.1186/1749-799x-7-38
• 发表时间: 2012-12-10
• 期刊: Journal of orthopaedic surgery and research
• 影响因子: 2.6
• 作者: Yokota K;Sakamoto A;Matsumoto Y;Matsuda S;Harimaya K;Oda Y;Iwamoto Y
• 通讯作者: Iwamoto Y

Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcoma.

• DOI: 10.1038/bjc.2012.579
• 发表时间: 2013-03-05
• 期刊: BRITISH JOURNAL OF CANCER
• 影响因子: 8.8
• 作者: Fujiwara-Okada, Y.;Matsumoto, Y.;Fukushi, J.;Setsu, N.;Matsuura, S.;Kamura, S.;Fujiwara, T.;Iida, K.;Hatano, M.;Nabeshima, A.;Yamada, H.;Ono, M.;Oda, Y.;Iwamoto, Y.
• 通讯作者: Iwamoto, Y.

miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor.

• DOI: 10.1186/1475-2867-13-21
• 发表时间: 2013-03-04
• 期刊: Cancer cell international
• 影响因子: 5.8
• 作者: Iida K;Fukushi J;Matsumoto Y;Oda Y;Takahashi Y;Fujiwara T;Fujiwara-Okada Y;Hatano M;Nabashima A;Kamura S;Iwamoto Y
• 通讯作者: Iwamoto Y

Impairment of p53 acetylation by EWS-Fli1 chimeric protein in Ewing Family Tumors

尤文家族肿瘤中 EWS-Fli1 嵌合蛋白对 p53 乙酰化的损害

• DOI: 10.1016/j.canlet.2012.01.018
• 发表时间: 2012-07-01
• 期刊: CANCER LETTERS
• 影响因子: 9.7
• 作者: Li, Yan;Li, Xu;Zhu, Yue
• 通讯作者: Zhu, Yue

Malignant peripheral nerve sheath tumors presenting as spinal dumbbell tumors: clinical outcomes and characteristic imaging features

• DOI: 10.1007/s00586-014-3467-8
• 发表时间: 2015-10-01
• 期刊: EUROPEAN SPINE JOURNAL
• 影响因子: 2.8
• 作者: Matsumoto, Yoshihiro;Endo, Makoto;Iwamoto, Yukihide
• 通讯作者: Iwamoto, Yukihide