Challenge to long-term durability of the material for dentin hypersensitivity with a remineralization ability

具有再矿化能力的牙本质过敏材料的长期耐久性挑战

• 批准号: 23592878
• 负责人: OKUYAMA Katsushi
• 金额: $ 3.41万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592878/
• 关键词: 象牙質知覚過敏症; う蝕抑制効果; 再石灰化; フッ素; 長期耐久性; フッ化物

The purpose of this research was to evaluate long-term durability of remineralization by materials for dentin hypersensitivity, which was expected the caries prevention effect. Large amount of fluoride release from fluoride-containing tooth paint material was shown in this study. Materials were applied to dentin surface for some periods. After then they were removed from dentin, and then samples were placed into oral environment for 4 weeks. Less demineralization and more fluorine concentration into dentin from fluoride-containing tooth paint materials were indicated than that of current materials. The higher fluorine concentration was shown longer application period. The fluorine bound or no-bound tooth was found by KOH (potassium hydroxide) treatment to tooth sample.

本研究的目的是评价牙本质过敏症材料再矿化的长期耐久性，以期达到防龋的效果。本研究发现含氟牙漆材料中有大量的氟化物释放。材料在牙本质表面涂抹了一段时间。然后将它们从牙本质中取出，然后将样品放入口腔环境中4周。与现有材料相比，含氟牙漆材料脱矿更少，进入牙本质的氟浓度更高。氟浓度越高，使用周期越长。用KOH(氢氧化钾)对牙样进行处理，发现有氟结合或无结合的牙齿。

项目成果

フッ素含有材料周囲う蝕エナメル質におけるストロンチウム分布の測定

含氟材料周围龋齿釉质中锶分布的测量

• 发表时间: 2011
• 作者: 若松里佳;竹中彰治;福島正義;興地隆史;船戸良基 ら
• 通讯作者: 船戸良基 ら

Fluoride uptake in human teeth from a fluoride-releasing thin layer after a long period of filling

长期填充后人类牙齿从释放氟化物的薄层中吸收氟化物

• 发表时间: 2011
• 期刊: International Journal of PIXE
• 作者: 坂上雄樹;竹中彰治;大墨竜也;長谷川泰輔;若松里佳;寺尾豊;興地隆史;Kubo S;H. Yamamoto et al
• 通讯作者: H. Yamamoto et al

Fluorine analysis of human enamel around fluoride-containing materials under different pH-cycling by μ-PIGE/PIXE system

• DOI: 10.1016/j.nimb.2011.02.042
• 发表时间: 2011-10-15
• 期刊: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
• 影响因子: 1.3
• 作者: Komatsu, H.;Yamamoto, H.;Oikawa, S.
• 通讯作者: Oikawa, S.

Fluoride uptake into human teeth from a fluoride-releasing thin layer after a long period of filling

长期填充后，人类牙齿从释放氟化物的薄层吸收氟化物

• 发表时间: 2011
• 期刊: International Journal of PIXE
• 作者: Yamamoto H;Iwami Y;Ebisu S;Komatsu H;Nomachi M;Sugaya Y;Yasuda K.
• 通讯作者: Yasuda K.

Fluorine analysis of human dentin surrounding resin composite after fluoride application by μ-PIGE/PIXE analysis

• DOI: 10.1016/j.nimb.2011.02.063
• 发表时间: 2011-10-15
• 期刊: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
• 影响因子: 1.3
• 作者: Okuyama, Katsushi;Komatsu, Hisanori;Sano, Hidehiko
• 通讯作者: Sano, Hidehiko