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Development of resin contained Ag-doped bioglass that inhibit MMP activity of dentin

Development of resin contained Ag-doped bioglass that inhibit MMP activity of dentin
开发含有树脂的掺银生物玻璃,可抑制牙本质的 MMP 活性
批准号:
23592894
负责人:
HASHIMOTO Masanori
金额:
$3.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
We evaluated the effects of a Ag-doped bioglass on inhibition of MMP and cytotoxicity to cells (RAW264). Ag-doped bioglass with 3% Ag2O inhibited the activity of MMP-2 and MMP-9 derived from dentin. However, this bioglass also showed cytotoxic effects. These findings may be attributed to the release of ions from bioglass. Further studies are required to optimize the bioglass composition for controlled release of ions to increase the inhibition effect of MMP activity and decrease the cytotoxicity.
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Evaluation of silver nanoparticle toxicity to RAW264.7 cells in a three-dimensional cell culture.
三维细胞培养物中银纳米颗粒对 RAW264.7 细胞的毒性评估。
DOI: 10.1166/jbt.2014.1141
发表时间: 2014
期刊: Journal of Biomaterials and Tissue Engineering
影响因子: 0.1
作者: [Hashimoto M, Toshima H, Yonezawa T, Kawai K, Iijima M, Endo K]
通讯作者: Endo K
酸化物ナノ粒子の細胞毒性と遺伝毒性
氧化物纳米粒子的细胞毒性和遗传毒性
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [橋本正則, 戸島洋和, 井田有亮, 建部二三, 遠藤一彦]
通讯作者: 遠藤一彦
水溶性モノマー結合銀ナノ粒子の細胞に対する影響
水溶性单体结合银纳米颗粒对细胞的影响
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [橋本正則, 戸島洋和, 米澤徹, 河合功治, 加我正行, 遠藤一彦]
通讯作者: 遠藤一彦
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [戸島洋和, 橋本正則, 長野二三, 井田有亮, 遠藤一彦]
通讯作者: 遠藤一彦
32
    iClay: A 3D real-time modeling system with tiny sensor nodes
    • 批准号:
      23240015
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $30.53万
    • 财政年份:
      2011
    • 负责人:
      HASHIMOTO Masanori
    • 依托单位:
    Development of self-healing material with ability of remineralization using nanobioglass
    • 批准号:
      20592384
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2008
    • 负责人:
      HASHIMOTO Masanori
    • 依托单位:
    Development of a sensor-node processor with four order of magnitude variable power dissipation
    • 批准号:
      19680002
    • 项目类别:
      Grant-in-Aid for Young Scientists (A)
    • 资助金额:
      $14.39万
    • 财政年份:
      2007
    • 负责人:
      HASHIMOTO Masanori
    • 依托单位:
    Development of self healing materials with remineralization(Bioglass for dental materials)
    海外基金